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Protein Alignment SmydA-2 and SMYD3

DIOPT Version :9

Sequence 1:	NP_649084.1	Gene:	SmydA-2 / 40075	FlyBaseID:	FBgn0036839	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	340	Identity:	87/340 - (25%)
Similarity:	141/340 - (41%)	Gaps:	60/340 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLG-----CHRNLLAPGKPRGNYHKCSSCS-W 116
            |..|||...::.||.:.:..||       :..:|.|     |.|.||  ||.:  ..:||.|. .
Human    15 GNGLRAVTPLRPGELLFRSDPL-------AYTVCKGSRGVVCDRCLL--GKEK--LMRCSQCRVA 68

  Fly   117 PLCGKECEDSV--HHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCM-HLKDKDPDAF 178
            ..|..:|:...  .||.||:.:.    ..|..|.|..         |.:|.|.: .|.|..|...
Human    69 KYCSAKCQKKAWPDHKRECKCLK----SCKPRYPPDS---------VRLLGRVVFKLMDGAPSES 120

  Fly   179 LKL---YNLEDHLKERLETPLYQVLRANLITF-------IKTVLGMKDWPEMDILRIAAILDTNT 233
            .||   |:||.:: .:|.....:.||..::||       |:....:.  |..|:....|.:..|:
Human   121 EKLYSFYDLESNI-NKLTEDKKEGLRQLVMTFQHFMREEIQDASQLP--PAFDLFEAFAKVICNS 182

  Fly   234 FEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRST 298
            |.:.....:.....|||..::::|.|.||....|:.. :::..|.|.|..||.|:|.|...|.::
Human   183 FTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGP-HLLLRAVRDIEVGEELTICYLDMLMTS 246

  Fly   299 IQRRVHLRQAKCFDCSCARCQ-DPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQ----LC 358
            .:||..||...||:|.|.||| ..::.....|.:...|.....:..:..|  .|.||.:    :|
Human   247 EERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEEL--KAHWKWEQVLAMC 309

  Fly   359 NFKRSAKDVVTSDAE 373
                  :.:::|::|
Human   310 ------QAIISSNSE 318

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.