DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-2 and Zmynd15

DIOPT Version :9

Sequence 1:	NP_649084.1	Gene:	SmydA-2 / 40075	FlyBaseID:	FBgn0036839	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001025100.1	Gene:	Zmynd15 / 574428	MGIID:	3603821	Length:	736	Species:	Mus musculus

Alignment Length:	242	Identity:	54/242 - (22%)
Similarity:	85/242 - (35%)	Gaps:	64/242 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASTSLTSCALCQAKASQL----CAACRNVVYCSREHQKEHWKK-----GHRSEC---QCFEIATN 54
            ||....:|.:|...:.::    |..|..|:||.....:..|::     .||..|   ..|.....
Mouse   300 ASLRARTCHVCHKHSFEVKLTPCPQCSAVLYCGEACLQADWRRCPDDVSHRFWCPRLSAFMERVG 364

  Fly    55 EVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLL----APGKPRGNYHKCSSCS 115
            |:.......|.:: ..|...|||.|      ||..|..|....|.    .||.||..:...||.|
Mouse   365 ELASLPFTYTAEV-TSETFNKEAFL------ASRGLTRGYWTQLSMLIPGPGAPRYPWGSTSSLS 422

  Fly   116 WPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLK 180
            ..|.|.          ..||:.|.. .:.:..||.|..|                         .
Mouse   423 CLLNGD----------PYQLLQGDG-PALMPPVPLEPPR-------------------------S 451

  Fly   181 LY-NLEDHLKER---LETPLYQVLRANL-ITFIKTVLGMKDWPEMDI 222
            |: :.:|:...|   |::|:..:|...| :.::.|.|..:.:||::|
Mouse   452 LFGSWQDYYTWRGLSLDSPMAVLLTYPLTVYYVITHLVPQSFPELNI 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:280009	10/45 (22%)
SmydA-2	NP_649084.1	SET	<246..291	CDD:214614
Zmynd15	NP_001025100.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..94
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	109..192
		zf-MYND	307..353	CDD:280009	10/45 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	556..583
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	696..736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900