DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-2 and smyd2a

DIOPT Version :10

Sequence 1:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_001013568.1 Gene:smyd2a / 541423 ZFINID:ZDB-GENE-050320-126 Length:435 Species:Danio rerio


Alignment Length:384 Identity:80/384 - (20%)
Similarity:137/384 - (35%) Gaps:85/384 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 GRHLRATRDIKIGEQILKEAP-----LVLGPKVASAPLCLGCHRNLLAPGKPRGNYH---KCSSC 114
            ||.|:|.:..|:|:.:. ..|     |.:..:......|......|...||.:..|:   :|...
Zfish    18 GRGLKAIKHFKVGDLVF-ACPAYAYVLTVNERGGRCECCFTRKEGLSKCGKCKQAYYCNVECQRG 81

  Fly   115 SWPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDP-DAF 178
            .||:          ||.||..|....    .|:.|.|..|..:.    ::|:..|..::.| :..
Zfish    82 DWPM----------HKLECSAMCAYG----ENWCPSETVRLVAR----IILKQKHQTERTPSERV 128

  Fly   179 LKLYNLEDHLKERLETPLYQVLRANLITFIKTVLGMKDWPEMDIL-RIAAILDTNTFEVRQPRER 242
            |.|..||.|| ::|:....::...::...........|:|:...| .:.|.::.|.|.:......
Zfish   129 LTLRELEAHL-DKLDNEKNEMNDTDIAALHHFYSRHLDFPDNAALTELIAQVNCNGFTIEDEELS 192

  Fly   243 RKIRALYPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQ 307
            ....||:|..|:::|.|.||:...:...:..| .|.::|...|.:..||...|..|..|...|:.
Zfish   193 HLGSALFPDVALMNHSCSPNVIVTYKGTVAEV-RAVQEINPEEEIFNSYIDLLYPTEDRIERLKD 256

  Fly   308 AKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDA 372
            :..|:|.|..|....                                      |..||..:....
Zfish   257 SYFFNCDCKECTSKS--------------------------------------KDEAKMEIRQKL 283

  Fly   373 ELQQELESLDKTTPVA---LEEFIYRHRADLHETNTHILQ----------AKYALTQLY 418
            .:..|.|.:.:....|   :|||   .||..::|.:.:|:          |.:|.|.:|
Zfish   284 SIPPEEEEIKQMVIYARNVIEEF---RRAKHYKTPSELLEICELSMEKMGAIFAETNVY 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:460312
SET_SMYD <227..318 CDD:380997 24/90 (27%)
smyd2aNP_001013568.1 SET 7..269 CDD:394802 63/271 (23%)
zf-MYND 52..90 CDD:460312 10/47 (21%)
TPR_12 382..>424 CDD:315987
Blue background indicates that the domain is not in the aligned region.

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