DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-2 and smyd5

DIOPT Version :10

Sequence 1:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_001004614.2 Gene:smyd5 / 447875 ZFINID:ZDB-GENE-040912-39 Length:415 Species:Danio rerio


Alignment Length:383 Identity:87/383 - (22%)
Similarity:137/383 - (35%) Gaps:112/383 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 CFEIA-TNEVLGRHLRATRDIKIGEQILKEAPLVLGP-------KVASAPLCLGCHRN------- 97
            |.::. .|.|.|:.|.|.:..|.|:.|..|.|||...       |..:...||.....       
Zfish    21 CVDVRFINNVKGKGLFAKKPFKKGDTIFIERPLVSSQFLWNALYKYRACEYCLRALETAEENARR 85

  Fly    98 ------LLAPG----KPRGNYHK-CSSCSWPLCGKECEDSV---HHKAECQLMSGSNFQSKIN-- 146
                  |:.|.    |.|.:.|: |..|....|..||..:.   :||..|...|..:....:|  
Zfish    86 LSGLPALILPHPELCKVRPDRHQACPQCQVMYCSSECRQAAMDQYHKILCLGPSNDDPDHPVNKL 150

  Fly   147 -------YVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLY--------NLEDHLKERLETPL 196
                   :.|.|    .|:..::..:.....:.:|.:.:.:|:        |.|:.:..:|....
Zfish   151 QDAWRSVHFPPE----TSSVMILAKMVATIKQTQDKERWQRLFTNFCSRTANEEEEIVHKLLGEK 211

  Fly   197 YQ----VLRANLITFIKTVLGMKDW--PEMDILRIAAILDTN-----TFEVRQ----------PR 240
            :|    :|| ||.|.......:..|  || ....:.:::.||     |..:.|          ||
Zfish   212 FQGQLGLLR-NLFTTALYEDRLSQWFTPE-GFRSLFSLVGTNGQGIGTSSLSQWVHACDALELPR 274

  Fly   241 ERRK-----IRALY-------------PGAAMI------SHDCVPNMRHRFDDDMNIVFL-AKRK 280
            ::|:     |..||             .|:.:.      :|.||||....|.::..::.| |...
Zfish   275 QQREQLDAFIDQLYKDIDKETGDFLNCEGSGLFLLQSSCNHSCVPNAEASFPENNFLLHLTALGD 339

  Fly   281 IAKGEILSISY---TQPLRSTIQRRVHLRQAKCFDCSCARC-----------QDPEEL 324
            |..||.:.|||   .|..||...|...||:...|.|||.:|           :|.||:
Zfish   340 IGPGEEICISYLDCCQRDRSRHSRHKILRENYLFICSCQKCLSQMDDADMTSEDEEEV 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:460312
SET_SMYD <227..318 CDD:380997 35/133 (26%)
smyd5NP_001004614.2 SET_SMYD5 21..383 CDD:380919 84/367 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 388..415 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.

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