Protein Alignment SmydA-2 and smyd1a

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_991103.2
• Gene: smyd1a / 321245
• ZFINID: ZDB-GENE-030131-9825
• Length: 485
• Species: Danio rerio
• Alignment Length: 533
• Identity: 127/533 - (23%)
• Similarity: 198/533 - (37%)
• Gaps: 149/533 - (27%)

  Fly    58 GRHLRATRDIKIGEQILKE---APLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWP-L 118
            ||.||.|||:..||.:..|   |.:||..  .|..:|..|.|..:.|       |:|:.|.:. .
Zfish    18 GRGLRGTRDLSAGEVVFAEASFAAVVLDS--LSLQVCHSCFRRQVNP-------HRCAQCKFAHY 73

  Fly   119 CGKECEDSV--HHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCM-----HLKDKDPD 176
            |.:.|:.:.  .|:.||..:      ..|...|.|..|        ::.|.:     |.......
Zfish    74 CDRTCQRAAWDEHRKECSAI------RNIGKAPNENVR--------LVARILWRIQKHTGLVSDS 124

  Fly   177 AFLKLYNLEDHLKERLETPLYQVLRANLITFIKTVLGMKDWPEMD-------ILRIAAILDTNTF 234
            ....|..|||||.......|.: |:.::.||...      ||:..       :..:..::..|.|
Zfish   125 QLTTLDMLEDHLSRMTPEDLKE-LKVDVKTFYTY------WPKKSKAVGEDYVSHLFGVISCNGF 182

  Fly   235 EVRQPRERRKIR-ALYPGAAMISHDCVPN----MRH--------RFDDDMNIVFLAKRKIAKGEI 286
            .:...|..:.:. .|:|...:::|||.||    :.|        .|.....|...|...|:.|:.
Zfish   183 TLSDQRGLQSVGIGLFPNLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQE 247

  Fly   287 LSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLK-CKAGKIISLNPLLNS 350
            |::||...|..:..|:..|:|...|||.|..|.:    |:.....|.:| .:.||    .|   |
Zfish   248 LTVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVN----GTKDELMTAVKPTEDGK----QP---S 301

  Fly   351 APWKCQLCNFKRSAKDVVTSDAELQQ----EL-----ESLDKTTPVALEEFIYRHRADLHETNTH 406
            |....||.:|  |.:.:|..:|...|    |:     |.|:|..||            ..:||.|
Zfish   302 AEVVKQLTDF--SLQALVKIEAARAQGNFHEVIRICRECLEKQDPV------------FADTNVH 352

  Fly   407 ILQ----AKYALT--QLYGSAPGFAMEELSGESLNRKLQLCEELLKL-----ADIFDGGWSIFRG 460
            :|:    |...|:  |.:..|.|:|...:.|            .:||     |.:   |.:|.|.
Zfish   353 VLRVLSTASEVLSFLQQFQEAAGYAQRMVDG------------YMKLYHPNNAQL---GMAIMRA 402

  Fly   461 NL------LIDMEEALVTQALR------------SKDPLDCEEKLRNAAEMLREIRNIMKHEPEM 507
            .:      ||:....|:.:|..            |||    .|.:|...||  |:|...::|...
Zfish   403 GVTHWHAGLIEAAHGLICRAYGILMITHGPHHPISKD----LEAMRRQTEM--ELRMFKQNEHVY 461

  Fly   508 QQLLLERQVILSS 520
            ..:   |:..|:|
Zfish   462 HSM---REAALTS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312
		SET_SMYD	<227..318	CDD:380997	27/103 (26%)
smyd1a	NP_991103.2	SET	9..279	CDD:394802	71/290 (24%)
		zf-MYND	52..90	CDD:460312	10/44 (23%)
		FxSxx_TPR	<321..435	CDD:468560	29/140 (21%)