Protein Alignment SmydA-2 and SmydA-4

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_572675.1
• Gene: SmydA-4 / 32034
• FlyBaseID: FBgn0030257
• Length: 532
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 148/499 - (29%)
• Similarity: 253/499 - (50%)
• Gaps: 34/499 - (6%)

  Fly    30 SREHQKEHWKKGHRSECQ----CFEIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPL 90
            |::.|::..|:...|..:    .:.:..:::.||:|.|.|.::.||.:::|.||.:||.|:..|:
  Fly    26 SKDKQEQQDKEQSPSPTEEKELPYRVEHSDIYGRYLVANRQLEAGETLIREEPLAIGPCVSGDPV 90

  Fly    91 CLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHH----KAECQLMSGSNFQSKINYVPGE 151
            ||||:.    |...:.:.::|..|:|||||..|....|.    :.||||      .::...|.||
  Fly    91 CLGCYH----PVSLKADQYRCPGCAWPLCGSTCAGLKHRHGHTETECQL------YAERRAVAGE 145

  Fly   152 --EERKESA-----YCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLETP-LYQVLRANLITFI 208
              .||...|     |.::|::|.:.|:..||:.|..:..:|.|.:||.:.. |::.....::..:
  Fly   146 LLTERAGPAEVRDLYELVMIVRILLLRQHDPEQFALIARMESHTEERRQNAVLWRHYEEKVVQRL 210

  Fly   209 KTVLGMKDWPEMDILRIAAILDTNTFEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFD-DDMN 272
            :....::|.....:..:..|||.|.||:.|  ...|.|.|||.|.:::|||.||..|..| ....
  Fly   211 RVTWQLEDLEAEQVHEVCGILDVNCFEIGQ--NGAKARTLYPSAFLLAHDCTPNTAHTDDPSSFE 273

  Fly   273 IVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCK 337
            |:....|::.:.|.|::||...|:.|::||..:.:.|.|.|.|.||.||.|||:...|..|..|:
  Fly   274 ILLRTSRRVREREALTLSYAYTLQGTLKRRAFMHEGKLFWCCCRRCSDPRELGTDCSALVCATCR 338

  Fly   338 AGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLDKTTPVALEEFIYRHRADLHE 402
            .|.:.:::||..:..|.|..|..|..|.:|......:..:||.:|......||.|:.|:|..|..
  Fly   339 TGSVRAVDPLQQTGDWACDRCAHKMGATEVERQLDRINNDLEDIDVHDIPGLENFLLRYRDVLRP 403

  Fly   403 TNTHILQAKYALTQLYGSAPGFAMEELSGESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDME 467
            .:..:|.|||:|.|:||...|:.:.::|.|.:.||...|.|.|::.|:.|.|.:..||.::.::.
  Fly   404 NHYLLLSAKYSLCQIYGRTEGYLLPQMSPEDIARKESYCREFLEIVDVLDPGLTRLRGLIMYELH 468

  Fly   468 E---ALVTQALRSK--DPLDCEEKLRNAAEMLREIRNIMKHEPE 506
            .   .|...|.:|.  ...:.:.:|:...::|:..|:|:..|||
  Fly   469 APVMVLAQSAFQSGQISRQEFQRRLKEVVKLLQVSRDILLMEPE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312	4/15 (27%)
		SET_SMYD	<227..318	CDD:380997	34/91 (37%)
SmydA-4	NP_572675.1	SET_SMYD	<230..319	CDD:380997	34/90 (38%)