Protein Alignment SmydA-2 and Smyd5

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001101340.1
• Gene: Smyd5 / 312503
• RGDID: 1309153
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 368
• Identity: 90/368 - (24%)
• Similarity: 131/368 - (35%)
• Gaps: 116/368 - (31%)

  Fly    58 GRHLRATRDIKIGEQILKEAPLVLGPKVASA----PLCLGCHRNL--------LAPGKP------ 104
            |:.|.||:.|:.||.|..|.|||....:.:|    ..|..|.|.|        ...|||
  Rat    33 GKGLFATQLIRKGETIFIERPLVASQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLPH 97

  Fly   105 ------RGNYHK-CSSCSWPLCGKECEDSV---HHKAECQLMSGSNFQSKIN----------YVP 149
                  |.:.|: |..|....|..||..:.   :|:..|...|..:.:..:|          |.|
  Rat    98 PELCSVRKDLHQNCPRCQVTYCSAECRLAAAEQYHQILCPGPSQDDPRHPLNKLQEAWRSVHYPP 162

  Fly   150 GEEERKESAYCVIMLLRCMHLKD-KDPDAFLKLYN-----------------LEDHLKERLETPL 196
                  |:|..::|......:|. ||.|.:::|::                 |.|..|.:||
  Rat   163 ------ETASIMLMARMVATVKQAKDKDHWVRLFSHFCSKTANEEEEIVHKLLGDKFKGQLE--- 218

  Fly   197 YQVLRANLITFIKTVLGMKDWPEMDILR-IAAILDTN-----TFEVRQ-----------PRERRK 244
               |...|.|.......:..|...|..| :.|::.||     |..:.|           |:||.:
  Rat   219 ---LLRRLFTEALYEETLSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDALELKPQEREQ 280

  Fly   245 ----IRALY-------------PGAAMI------SHDCVPNMRHRFDDDMNIVFL-AKRKIAKGE 285
                |..||             .|:.:.      :|.||||....|.::..::.: |...|..||
  Rat   281 LDTFIDQLYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIEPGE 345

  Fly   286 ILSISY---TQPLRSTIQRRVHLRQAKCFDCSCARC----QDP 321
            .:.|||   .|..||...|...||:...|.|||.:|    .||
  Rat   346 EICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADDP 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312
		SET_SMYD	<227..318	CDD:380997	35/133 (26%)
Smyd5	NP_001101340.1	SET_SMYD5	22..384	CDD:380919	88/362 (24%)
		zf-MYND	101..136	CDD:480929	8/34 (24%)