DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-2 and Smyd1

DIOPT Version :10

Sequence 1:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_001100065.1 Gene:Smyd1 / 297333 RGDID:1305105 Length:490 Species:Rattus norvegicus


Alignment Length:551 Identity:115/551 - (20%)
Similarity:200/551 - (36%) Gaps:152/551 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 EIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSC 114
            |:.|:|..||.|:||::....:.|..|.  .....|..:.:...||...    |.:...|:|..|
  Rat    10 EVFTSEGKGRGLKATKEFWAADVIFAER--AYSAVVFDSLINFVCHTCF----KRQERLHRCGQC 68

  Fly   115 SWP-LCGKECEDS--VHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKD-- 174
            .:. .|.:.|:..  ::||.||..:      .:...||.|..|        :..|.|...:::  
  Rat    69 KFAHYCDRTCQKDAWLNHKNECSAI------KRYGKVPNENIR--------LAARIMWRVEREGT 119

  Fly   175 ---PDAFLKLYNLEDHLKERLETPLYQVLRANLITFIKTVLGMKDWPEMD-------ILRIAAIL 229
               ....:.:.:|::|: |.......:.||.::.||::.      ||...       |..|..::
  Rat   120 GLTEGCLVSVDDLQNHV-EHFGEEEQKELRVDVDTFLQY------WPPQSQQFSMQYISHIFGVI 177

  Fly   230 DTNTFEVRQPRERRKIR-ALYPGAAMISHDCVPN------------MRHRFDDDMNIVFLAKRKI 281
            :.|.|.:...|..:.:. .::|...:::|||.||            ::..|...|.|...|..||
  Rat   178 NCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKI 242

  Fly   282 AKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNP 346
            ::||.|::||...|..:.:||..|::...|||||..||..            ||......:..:|
  Rat   243 SEGEELTVSYIDFLHLSEERRQQLKKQYYFDCSCEHCQKG------------LKDDLFLAVKEDP 295

  Fly   347 LLNSAPWKCQLCNFKRSAKDVVTSDAELQQE-LESLDKTTPVALEEFIYRHRADLHETNTHILQA 410
                           :.:::||....:..:: ||.:||    |..|.:|.....|........:.
  Rat   296 ---------------KPSQEVVKEMTQFSKDTLEKIDK----ARSEGLYHEVVKLCRECLEKQEP 341

  Fly   411 KYALTQLYGSAPGFAMEELSGESLNRKLQLCEELLKLADIF-----------DG----------- 453
            .:|.|.||               :.|.|.:..|:|.....|           ||           
  Rat   342 VFADTNLY---------------VLRLLSIVSEVLSYLQAFEEASHYARRMVDGYMKLYHHNNAQ 391

  Fly   454 -GWSIFRGNLL------IDMEEALVTQALR------------SKDPLDCEEKLRNAAEMLREIRN 499
             |.::.|..|.      |::...::.:|..            :||    .|.:|...||  |:|.
  Rat   392 LGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKD----LEAMRMQTEM--ELRM 450

  Fly   500 IMKHE---PEMQQLLLERQVILSSALERFEP 527
            ..::|   .:|::..|..|.:...|....||
  Rat   451 FRQNEFMYHKMREAALNNQPMQVMAEPSNEP 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:460312
SET_SMYD <227..318 CDD:380997 29/103 (28%)
Smyd1NP_001100065.1 SET_SMYD1 7..281 CDD:380924 70/297 (24%)
zf-MYND 52..90 CDD:460312 10/41 (24%)
Blue background indicates that the domain is not in the aligned region.

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