DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-2 and Smyd5

DIOPT Version :10

Sequence 1:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_659167.2 Gene:Smyd5 / 232187 MGIID:108048 Length:416 Species:Mus musculus


Alignment Length:369 Identity:86/369 - (23%)
Similarity:139/369 - (37%) Gaps:111/369 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 NEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASA----PLCLGCHRNL--------LAPGKP-- 104
            :.:.|:.|.||:.|:.||.|..|.|||....:.:|    ..|..|.|.|        ...|||  
Mouse    29 DSIKGKGLFATQLIRKGETIFIERPLVAAQFLWNALYQYRACDHCLRALEKAEENAQRLTGKPSQ 93

  Fly   105 ----------RGNYHK-CSSCSWPLCGKECEDSVHHKAECQLMSGSNFQSK------------IN 146
                      |.:.|: |..|....|..||..:...:....|..|.:...:            ::
Mouse    94 ILPHPELCSVRKDLHQNCPHCQVMYCSAECRLAAAEQYHQILCPGPSHDPRHPLNKLQEAWRSVH 158

  Fly   147 YVPGEEERKESAYCVIMLLRCMHLKD-KDPDAFLKLYNLEDHLKERL----ETPLYQVLRANLIT 206
            |.|      |:|..::|......:|. ||.|.:::|:|   |...|.    :..::::|:.....
Mouse   159 YPP------ETASIMLMARMVATVKQAKDKDHWVRLFN---HFCSRTANQEQAIVHKLLKGKFKD 214

  Fly   207 FIKTVLGM-KD---------W--PEMDILRIAAILDTN-----TFEVRQ-----------PRERR 243
            .::.:||: |:         |  || ....:.|::.||     |..:.|           |::|.
Mouse   215 QLELLLGLFKEALYEEALSLWFTPE-GFRSLFALVGTNGQGIGTSSLSQWVHACDALELTPQDRE 278

  Fly   244 K----IRALY-------------PGAAMI------SHDCVPNMRHRFDDDMNIVFL-AKRKIAKG 284
            :    |..||             .|:.:.      :|.||||....|.::..::.: |...|..|
Mouse   279 QLDTFIDQLYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFVLHVTALEDIKPG 343

  Fly   285 EILSISY---TQPLRSTIQRRVHLRQAKCFDCSCARC----QDP 321
            |.:.|||   .|..||...|...||:...|:|||.:|    .||
Mouse   344 EEICISYLDCCQRERSRHSRHKILRENYLFNCSCPKCLAEADDP 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:460312
SET_SMYD <227..318 CDD:380997 34/133 (26%)
Smyd5NP_659167.2 SET_SMYD5 22..383 CDD:380919 84/363 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 383..416 2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

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