Protein Alignment SmydA-2 and set-30

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_508850.2
• Gene: set-30 / 180772
• WormBaseID: WBGene00022499
• Length: 560
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 122/572 - (21%)
• Similarity: 189/572 - (33%)
• Gaps: 211/572 - (36%)

  Fly    76 EAPL-VLG-PKVASAP----------------------LCLGCHRNLLAPGKPRGNYHKCSSCS- 115
            :||| |:| .|:.|.|                      .|||.:..|           .|..|.
 Worm     5 DAPLEVVGVEKIGSKPRSKEFYPFAYSLLDCTKDDYCWTCLGENVEL-----------TCEQCKV 58

  Fly   116 WPLCGKECEDS--VHHKAECQLMSGSNFQSKINYVP--GEEERKESAYCVIMLLRC------MHL 170
            ...|.|:||.|  :.||.||         ..:...|  ..:||        ||:|.      :|.
 Worm    59 AKFCSKQCETSGAIDHKYEC---------GPLKKCPDLNTDER--------MLIRIVGRYKDIHS 106

  Fly   171 -KDKDPDAFLKLYNLEDHLKERLETPLYQVLRANLITFIKTVLGMKDWPE-MDILRIAAILDTN- 232
             |||..|.|   ||..:..:..:|      :..:.....|....||.:.: .|  |:....|||
 Worm   107 GKDKSIDGF---YNNRESKRSVME------IWEHCADMKKDENAMKSFKKTYD--RVKQFGDTNH 160

  Fly   233 ------TFEV--RQPRERRKI----------RALYPGAAMISHDCVPN-----------MRHRFD 268
                  ||::  |....|..|          :.||.......|.|.||           :|...|
 Worm   161 LMDEEVTFQLHSRNFINRHSISNVDYLREIGKGLYLDLCKYDHSCRPNAIYSCNGIVAKLRALHD 225

  Fly   269 D-DMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQT 332
            : |:..|          |....:|.:.....||||..|::...|:|.|.||.||::  ::..:..
 Worm   226 NVDLENV----------ETTHYTYIELPPCKIQRRHMLKETWYFECHCERCDDPDD--NWLTSVL 278

  Fly   333 CLKC----KAGKIISL-------NPLLNSAPWKCQLCNFKRSAKDVVTSDAE-----------LQ 375
            |..|    :..|.|.|       ||  .:....|..|:        .|.|.|           ::
 Worm   279 CPVCISKTEYRKTIKLHGPEAYANP--ETLEIVCDRCS--------TTLDREYIFMALDGMRTIR 333

  Fly   376 QELESLDKTT--PVALEEFIYRHRADLHE-----TNTHILQAKYALTQLYGSAPGFAMEELSGES 433
            :.:|..:..|  |:.|.: ||:.....:|     :|.:..|...|:..|           :|..|
 Worm   334 RTVEGAEDETKDPIELLK-IYQGALMTYERILPMSNAYFCQLIAAMIPL-----------ISRVS 386

  Fly   434 LNRKLQL---------CEEL-----------------------LKLADIFDGGWSIFRGNLLID- 465
            :.:|.:|         ||..                       |:||:..|....:...:.::|
 Worm   387 MTKKERLVASLDLHLKCETFVRYVYRHAHPSKAMHFLQMGQLHLELANDKDAARCLIEAHRIMDY 451

  Fly   466 ---MEEALVTQALRSKDPLDCEEKLRNAAEMLREIRNIMKHEPEMQQLLLER 514
               .:..|..|   :|..:|  ..|.:..:..|...|::...||.:|.|.||
 Worm   452 LFGADHFLSKQ---TKGFMD--HALSSLMQFQRNFVNVLDRVPEAKQALEER 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312
		SET_SMYD	<227..318	CDD:380997	28/121 (23%)
set-30	NP_508850.2	zf-MYND	41..78	CDD:460312	13/47 (28%)
		SET_SMYD	<179..266	CDD:380997	21/96 (22%)