DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-2 and Smyd3

DIOPT Version :10

Sequence 1:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster
Sequence 2:XP_061511104.1 Gene:Smyd3 / 1279922 VectorBaseID:AGAMI1_011343 Length:458 Species:Anopheles gambiae


Alignment Length:517 Identity:114/517 - (22%)
Similarity:180/517 - (34%) Gaps:153/517 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 TSCALCQAKASQL-CAACRNVVYCSREHQKEHWKKGHRSECQCFEIATNEVLGRHLRATRDIKIG 70
            |.|..|..:...: |:.|..|.||.|..|||.| ..|:.||:                       
Mosquito    32 TRCDRCFKETKVMKCSNCLYVRYCGRSCQKEAW-SDHKEECE----------------------- 72

  Fly    71 EQILKEAPLVLGPKVASAPLCLG-CHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQ 134
                |...|..|..|.||.|.:. ..|.||..|.....|:               .|..::..|.
Mosquito    73 ----KLKALPPGLVVPSAALMIARIVRRLLKGGDTHKGYY---------------TSKQYRKFCD 118

  Fly   135 LMSGSNFQSKINYVPGEEE-RKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLETPLYQ 198
            ||            |.||. |.:|               |..:.|..||.:...|.:....|   
Mosquito   119 LM------------PHEENIRADS---------------KRMEHFGTLYVVLQRLLDEASRP--- 153

  Fly   199 VLRANLITFIKTVLGMKDWPEMDILRIAAILDTNTFEVRQPRERRKIRALYPGAAMISHDCVPNM 263
                               .:.::|||...:..|||.:...........:|.||::|.|.|.||:
Mosquito   154 -------------------TKAELLRIYGKMCINTFNILDAEMSTIGTGMYIGASIIDHSCRPNV 199

  Fly   264 RHRFDDDMNIVFL----AKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEEL 324
            ...||.:...:.|    .::::..|: |.|||...:.:|..||..|.:...|.|:|.||:|.:|.
Mosquito   200 VVSFDGETLRMRLLEDYPEQELDFGK-LFISYIDLIDTTEVRREQLAERYYFHCACERCRDEQEQ 263

  Fly   325 GSFAGAQTC--LKCKAGKIISLNPLLNSAPWKC-------------QLCNFKR----SAKDVVTS 370
            ... .|..|  ..|......|.:..||..| .|             ::.:|.|    ..|.|.::
Mosquito   264 KRM-NAAACPNTTCHEPLDFSDSEQLNQCP-ACGTAVTHSDREAFAEISSFTRDHLAQMKSVAST 326

  Fly   371 DAELQQELESLDKTTPVALEEFIYRHRADLHETNT--HILQAKYALTQLYGSAPGFAMEELSGES 433
            |.::.:  ..|||...|.       ||.::|...|  :.:::..:| :.:..|.|:.:..|.|  
Mosquito   327 DLDVSR--LCLDKQANVL-------HRYNVHHIKTLDNAMESALSL-EKWPEATGYGLRLLDG-- 379

  Fly   434 LNRKLQLCEELLKLADIFDGGWSIFRGNLLIDMEEALVTQALRSKDPLDCEEKLRNAAEMLR 495
            ..:.......||.|..:..|...::         :...|:||:         :|:.||::||
Mosquito   380 FRQYYSPYHPLLGLTYLKVGKLQLY---------QCQFTEALK---------QLQQAAKILR 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:460312 13/37 (35%)
SET_SMYD <227..318 CDD:380997 26/94 (28%)
Smyd3XP_061511104.1 None

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