Protein Alignment SmydA-2 and SmydA-5

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: XP_311564.5
• Gene: SmydA-5 / 1272663
• VectorBaseID: AGAMI1_015164
• Length: 557
• Species: Anopheles gambiae
• Alignment Length: 567
• Identity: 166/567 - (29%)
• Similarity: 273/567 - (48%)
• Gaps: 73/567 - (12%)

  Fly     8 SCALCQAKASQLCAACRNVVYCSREHQKEHWKKGHRSEC-QCFEIATNEVLGRHLRATRDIKIGE 71
            :|..|...|...||.|:.|.||:.:|||:|||..|:.|| :.:|:..::.:|||..||:.|:...
Mosquito     4 NCGYCGVPAKLKCAGCQQVYYCNPDHQKKHWKAKHKHECVKPYELTKSDEIGRHFVATKTIEKDT 68

  Fly    72 QILKEAPLVLGPKVASAPL--------CLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECE---D 125
            .:..|.|||:|||...|..        |:||..:.     |.|.:: |..|.||.|..:|.   :
Mosquito    69 ILFSENPLVIGPKWNLADYEQRSTVVPCVGCFTDC-----PLGQFY-CEFCRWPACKPDCPGLGN 127

  Fly   126 SVHHKAECQLM-------SGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYN 183
            |..|..||.::       .|.:.:...:|.         .|..:::|:|:.|:.::.|.|.:|.|
Mosquito   128 SNLHGLECGVLRFGRPPKPGDDPEMFFDYY---------RYDALLVLKCLALQIRNADLFDQLIN 183

  Fly   184 LEDHLKERLETPLYQVLRANLITFI----------------KTVLGMKDWPEMDILRIAAILDTN 232
            ||.|...|..:..|......:::::                |.||.|.|...:.:  |..||:.|
Mosquito   184 LESHYNARKNSRYYADTDERVVSYLFRNFLDPLQKLERKEGKVVLKMCDRKTLHM--IGGILEVN 246

  Fly   233 TFEVRQPRER-RKIRALYPGAAMISHDCVPNMRHRFD--DDMNIVFLAKRKIAKGEILSISYTQP 294
            ...:  |... |:|..|||...::.|:|:||..:.||  ..|.:.|.|.|.|.|||.::.:||..
Mosquito   247 AMII--PLSNGREICGLYPMGCLLEHNCMPNSFYTFDCSKGMKLTFKAGRDIQKGEHITTTYTHS 309

  Fly   295 LRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCK----AGKIISLNPLLNSAPWKC 355
            |..|..||.||:..|.|.|.|:||.||.|.|:|..|..|:..:    .|..:.:|||...:.|||
Mosquito   310 LWGTQLRREHLKTNKYFACKCSRCSDPTEFGTFLSALRCMGIENEPCGGFQLPINPLAEDSDWKC 374

  Fly   356 QLCNFKRSAKDVVTSDAELQQELESL--DKTTPVALEEFIYRHRADLHETNTHILQAKYALTQLY 418
            ..|..:.:...|....:::.:|::.:  .|::....|..|::.:..||..:.|:...|::|.|:|
Mosquito   375 NRCPVQITHDQVNFLMSKIGEEVDDVMSRKSSVKEFENLIHKLQNFLHPNHFHLQTLKHSLIQMY 439

  Fly   419 GSAPGFAMEELSGESLNRKLQLCEELLKLADIFDG---GWSIFRGNLLIDMEEALVTQALR--SK 478
            |..||..:.|||.|.|..||::|.|:|.:.::.|.   ..|::...:|::...||:....|  |.
Mosquito   440 GRFPGHRLSELSDEILRTKLKMCHEMLTIIEVLDPESFRLSLYASVILLEQHAALIELHKRQNSL 504

  Fly   479 DPLDCEEKLRNAAEMLREIRNIMKHEPEMQQ--LLLERQVILSSALE 523
            ...:.::.|..|.:.|...:||:::|....|  .|:|:   :.||||
Mosquito   505 TASNVKDALSEALQSLVRAKNILRNEMGTLQGKKLMEQ---IESALE 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312	16/36 (44%)
		SET_SMYD	<227..318	CDD:380997	35/93 (38%)
SmydA-5	XP_311564.5	None