Protein Alignment SmydA-2 and SMYD5

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_006053.2
• Gene: SMYD5 / 10322
• HGNCID: 16258
• Length: 418
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 88/362 - (24%)
• Similarity: 130/362 - (35%)
• Gaps: 114/362 - (31%)

  Fly    58 GRHLRATRDIKIGEQILKEAPLVLGPKVASA----PLCLGCHRNL--------LAPGKP------ 104
            |:.|.||:.|:.||.|..|.|||....:.:|    ..|..|.|.|        ...|||
Human    33 GKGLFATQLIRKGETIFVERPLVAAQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLPH 97

  Fly   105 ------RGNYHK-CSSCSWPLCGKECE---DSVHHKAEC-------QLMSGSNFQS---KINYVP 149
                  |.:.|: |..|....|..||.   ...:|:..|       .|...:..|.   .|:|.|
Human    98 PELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRSIHYPP 162

  Fly   150 GEEERKESAYCVIMLLRCMHLKD-KDPDAFLKLYN-----------------LEDHLKERLETPL 196
                  |:|..::|......:|. ||.|.:::|::                 |.|..|.:||
Human   163 ------ETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKGQLE--- 218

  Fly   197 YQVLRANLITFIKTVLGMKDWPEMDILR-IAAILDTN-----------------TFEVRQPRERR 243
               |...|.|.......:..|...|..| :.|::.||                 |.|:: |::|.
Human   219 ---LLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELK-PQDRE 279

  Fly   244 KIRA----LY-------------PGAAMI------SHDCVPNMRHRFDDDMNIVFL-AKRKIAKG 284
            ::.|    ||             .|:.:.      :|.||||....|.::..::.: |...|..|
Human   280 QLDAFIDQLYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPG 344

  Fly   285 EILSISY---TQPLRSTIQRRVHLRQAKCFDCSCARC 318
            |.:.|||   .|..||...|...||:...|.|||.:|
Human   345 EEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKC 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312
		SET_SMYD	<227..318	CDD:380997	34/134 (25%)
SMYD5	NP_006053.2	SET_SMYD5	22..384	CDD:380919	88/362 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	385..418