Protein Alignment CG3808 and trmt2a

DIOPT Version :9

• Sequence 1: NP_649083.2
• Gene: CG3808 / 40074
• FlyBaseID: FBgn0036838
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_956223.1
• Gene: trmt2a / 334936
• ZFINID: ZDB-GENE-030131-6876
• Length: 619
• Species: Danio rerio
• Alignment Length: 611
• Identity: 226/611 - (36%)
• Similarity: 338/611 - (55%)
• Gaps: 52/611 - (8%)

  Fly     9 PADGVVNSIE--TEEISENVVK----ADETTLANGEDE------AGKAGEEYAYLERNEFTSEIF 61
            || |::.|.|  .||::|..::    .|.|...|.|:|      ...||:.|.|::.:.|||||:
Zfish    11 PA-GLLPSAEEKPEELTEEKIQENEPEDSTEKKNQENEPEAAEGQAAAGDVYRYIKEDLFTSEIY 74

  Fly    62 KVEVKNM-GYFGIGEFKKLLRNTLKFDVTKIKAPTRKEFAFVCFRSQEDQQRALEILNGYKWKGK 125
            |||::|: .|.|..:.||.| |....:..|||...|::||||.|::||::.:|::.::|.:||..
Zfish    75 KVEIQNLPKYIGFNDLKKFL-NKHGINPHKIKLLGRQKFAFVTFKNQEERDKAMKAVHGMQWKSN 138

  Fly   126 VLKAHVAKASADPLQKKRAAEEQESERKPKKQRTA-----------------VEATCPLSHIAYD 173
            ||...:||..|||:.|||..||:....:|..:|..                 ..|..||..:.|:
Zfish   139 VLSVRLAKPKADPILKKRKQEEEADSGQPGAERNTGSQEAEKEEEEPPSIQIANAVTPLWKVPYE 203

  Fly   174 QQIKQKSEEMSALLAKYTQELRKVNPRAKPHL----DKFQ-----FHEVLPSPTVNGYRNKNEFT 229
            :|:..|.:|:..:|.|..:|:...|....|.|    :|..     ...:.|||...|||||.||.
Zfish   204 EQLMMKEKEVEGVLQKLAREIGNNNKAMLPWLFVQKEKHNKMCCPLEAIRPSPLQTGYRNKCEFV 268

  Fly   230 VGKNSVGE-VVVGFRLGCYSDGSVEVAEVADLPHLPEQAKWAARSFQDLVRKSKFLPFNPDGNIG 293
            :|..:.|| ..||||||.|..||..|...::..::..:||...:.||..:|.:.:..::|:...|
Zfish   269 IGVGADGEDRTVGFRLGKYKGGSCAVVSPSETTNVCSEAKRVVQCFQQFIRTTPYAVYSPETYEG 333

  Fly   294 HFRQLMVRCSSATGELMLVAGIYSSNLSEDEQVELKQELKSFYEDLANDAPYKCSSLYYQDVKHR 358
            |:|||.|| ::...:.|.:.......|.|.|..||||.|..::.: ........:|||:..:..|
Zfish   334 HWRQLTVR-TTRLKQTMAMVFFNPQKLQEKELEELKQNLGQYFTE-GEGKECAVTSLYFVRMGQR 396

  Fly   359 -EAGQTINPVEHISGSTHITDTIQGLQFRISPLAFFQINTEGANVLYQKAIDLVAPTKDTTMLDI 422
             .||....|.||::|...|.:.:.||:|||||.:|||.||..|.:||....:.....:|:|:||:
Zfish   397 TSAGTEDLPCEHVTGEEWIHEELLGLKFRISPHSFFQTNTPAAEILYSAVGEWAQLDQDSTVLDV 461

  Fly   423 CCGTGTITLAFAKHCKKVMGVEIVPDAIKDAEFNAEANGIKNAKFFTGNADDFIKSMVREALYDQ 487
            |||||||.::.||..|||:|:|:..:|:||||.||:|||:.|.:|..|.|:|...:::...:
Zfish   462 CCGTGTIGISLAKRVKKVIGIELCQEAVKDAEANAKANGLTNVEFHCGKAEDVFPTILNAVV--- 523

  Fly   488 EPGKPLDLIAVVDPPRAGLHHRSIAAIRSADAINRLVYVSCNPHSAKRNFIELARPESKQYKGEP 552
               .| ::.|:|||||||||.:.|.|||.|:.:.|||||:||..:|..|||:|.|..|.:.:|..
Zfish   524 ---SP-NVTAIVDPPRAGLHSKVILAIRKAEHLKRLVYVACNAKAAMNNFIDLCRAPSNRVRGAA 584

  Fly   553 FYPKSAVAVDMFPHTMHTELVILFER 578
            |.|..|:|||:||.|||.|.::||||
Zfish   585 FRPVKAMAVDLFPQTMHCETILLFER 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3808	NP_649083.2	RRM_TRMT2A	56..134	CDD:240885	33/78 (42%)
		TrmA	57..571	CDD:225174	203/542 (37%)
		AdoMet_MTases	276..579	CDD:302624	124/304 (41%)
trmt2a	NP_956223.1	RRM_TRMT2A	69..147	CDD:240885	33/78 (42%)
		RRM	<71..>160	CDD:223796	38/89 (43%)
		TrmA	201..604	CDD:225174	157/411 (38%)
		AdoMet_MTases	<410..610	CDD:302624	95/206 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573880
Domainoid	1	1.000	188	1.000	Domainoid score	I3252
eggNOG	1	0.900	-	-		E1_COG2265
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7374
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2097
OMA	1	1.010	-	-		QHG54357
OrthoDB	1	1.010	-	-		D248059at2759
OrthoFinder	1	1.000	-	-		FOG0001356
OrthoInspector	1	1.000	-	-		oto40132
orthoMCL	1	0.900	-	-		OOG6_100839
Panther	1	1.100	-	-	LDO	PTHR45904
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4037
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770