Protein Alignment CG3808 and Trmt2b

DIOPT Version :9

• Sequence 1: NP_649083.2
• Gene: CG3808 / 40074
• FlyBaseID: FBgn0036838
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001161466.1
• Gene: Trmt2b / 215201
• MGIID: 2442530
• Length: 493
• Species: Mus musculus
• Alignment Length: 483
• Identity: 174/483 - (36%)
• Similarity: 254/483 - (52%)
• Gaps: 44/483 - (9%)

  Fly   117 LNGYKWKGK----VLKAHVAKASADPLQKKRAAEEQESERKPKKQRTAVEATCPLSHIAYDQQIK 177
            |.|..:||.    :.|.|   .|....|||     |...|....|....:...||..::|:.|:|
Mouse    34 LLGRAYKGSFTSVIAKKH---PSRQKYQKK-----QRHCRDDSWQERLADVVTPLWRLSYEAQLK 90

  Fly   178 QKSEEMSAL---LAKYTQELRKVNPRAKPHLD---KFQFHEVLPSPTVNGYRNKNEFTVGKNSVG 236
            .|.|....|   |..:.:.|..|:.....|..   :...|.::||||..|||||:.|:|.::..|
Mouse    91 VKFEAQKKLLQSLESHLKVLHGVSDTVAAHQSEGLRCLLHPIIPSPTTTGYRNKSTFSVYRSPDG 155

  Fly   237 E-VVVGFRLGCYSDGSVEVAEVADLPHLPEQAKWAARSFQDLVRKSKFLP---FNPDGNIGHFRQ 297
            . ..||:.||.:.||:|.......|.::||:....|:.::..:|:|...|   |: :|  ||:|:
Mouse   156 NPKTVGYYLGTWKDGNVVCLPCNHLKNIPEKHSQVAQYYEVFLRQSSVEPCLLFH-EG--GHWRE 217

  Fly   298 LMVRCSSATGELMLVAGIYSSNLSEDEQVELKQELKSFYEDLANDAPYKCSSLYYQDVKHREAGQ 362
            |:|| ::..|..|.:...:...|||:|....|..||.|:.. ...|..:.:|||:|:........
Mouse   218 LVVR-TNRQGHTMAIVTFHPQGLSEEEVCVQKVTLKDFFTK-GPGAICELTSLYFQESTMTRCSH 280

  Fly   363 TINPVEHISGSTHITDTIQGLQFRISPLAFFQINTEGANVLYQKAIDLVAPTKDTTMLDICCGTG 427
            ..:|.:.:.|..||.:.:.||:.||||.|||||||.||.:||:...:|.....::.:||||||||
Mouse   281 QQSPYQLLFGEPHIFEDLLGLKIRISPDAFFQINTAGAEMLYRIIGELSGVNSESLLLDICCGTG 345

  Fly   428 TITLAFAKHCKKVMGVEIVPDAIKDAEFNAEANGIKNAKFFTGNAD----DFIKSMVREALYDQE 488
            .|.|:.|:...:|.|:|:|..|::||.:.|..||:.|.:|..|.|:    ..:||...|.|
Mouse   346 VIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPQLLKSQKDEKL---- 406

  Fly   489 PGKPLDLIAVVDPPRAGLHHRSIAAIRSADAINRLVYVSCNPH-SAKRNFIELARP--ESKQYKG 550
                  .:|||:|.|||||:|.:.|||:...|:.||:|||.|| .:.||||||..|  .:||..|
Mouse   407 ------TVAVVNPARAGLHYRVVRAIRNCRTIHTLVFVSCKPHGESTRNFIELCCPPNSAKQLLG 465

  Fly   551 EPFYPKSAVAVDMFPHTMHTELVILFER 578
            :||..:.||.||:||||.|.|||:||.|
Mouse   466 DPFVLREAVPVDLFPHTPHCELVLLFTR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3808	NP_649083.2	RRM_TRMT2A	56..134	CDD:240885	6/20 (30%)
		TrmA	57..571	CDD:225174	168/474 (35%)
		AdoMet_MTases	276..579	CDD:302624	125/313 (40%)
Trmt2b	NP_001161466.1	TrmA	83..486	CDD:225174	153/417 (37%)
		AdoMet_MTases	<290..490	CDD:302624	95/209 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54357
OrthoDB	1	1.010	-	-		D248059at2759
OrthoFinder	1	1.000	-	-		FOG0001356
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1692
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860