Protein Alignment CG3808 and trm-2A

DIOPT Version :9

• Sequence 1: NP_649083.2
• Gene: CG3808 / 40074
• FlyBaseID: FBgn0036838
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_503353.2
• Gene: trm-2A / 186775
• WormBaseID: WBGene00019241
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 188/648 - (29%)
• Similarity: 305/648 - (47%)
• Gaps: 125/648 - (19%)

  Fly    10 ADGVVNSIETEEISENVVKADETTLANGEDEAGKAGEEYAYLERNEFTSEIFKVEVKNMGYF-GI 73
            ||.|....||.|::..|                          :.|...::.::.:||:..| |.
 Worm     2 ADPVDIKTETPELTPEV--------------------------KEEKAIDLDRIHIKNIPTFIGF 40

  Fly    74 GEFKKLLRNTLKFDVTKIKAPTRKEFAFVCFRSQEDQQRALEILNGYKWKGKVLKAHVAKASADP 138
            .:|||:|...|. ||...|.....::|:|.|.:.||.|:|:.:::||.:|..:|.|.:|   |..
 Worm    41 KQFKKVLEKILG-DVKSKKVRHMSDYAYVTFETPEDAQKAINLVDGYDYKKFILSAQLA---ATE 101

  Fly   139 LQKKRAAEEQESERKPKKQRTAVEATCPLSHIAYDQQIKQKSEEMSALLAKYTQEL--RKVNPRA 201
            ::..|.|..:.:|  |.:|:||.|:..||:.:.|.:|::.|.:....::.|..::|  .||
 Worm   102 VKSFRPANPENTE--PAQQKTARESVTPLAEMEYGKQLELKQQNSVGVVEKLYRQLIQNKV---- 160

  Fly   202 KPHLDK-FQF-----HEVLPSPTVNGYRNKNEFTVGKNSVGEVVVGFRLGCYSDGSVEVAEVADL 260
             .||.| .||     .|:||:|...|||||.|||:|.:..||:.|||..|.:|.....|....|:
 Worm   161 -AHLGKQTQFRDRVLREILPAPKTAGYRNKCEFTIGHDLNGEICVGFVGGRFSKNQHFVIPPVDV 224

  Fly   261 PHLPEQAKWAARSFQDLVRKSKFLPFNPDGNIGHFRQLMVRCSSATGELMLVAGIY--SSNLSED 323
            ..:..|.........:.|::|...|||.....|.:|.|.:|  ...|::||:..::  ...:...
 Worm   225 DIVSTQMMAIVGDVHEFVKESALEPFNEFDRKGFWRMLTIR--EFGGDVMLIFTVFPLEDGVERM 287

  Fly   324 EQVELKQELKSFYEDLANDAPYKCSSLYYQDVKHREAGQTINPVEHISGSTHITDTIQGLQFRIS 388
            |:::.|.|.:....:...:..|:..|:|:|.:.|  ...|.| .:.|.|:.:|.:::...:||:|
 Worm   288 EEIQKKIETRFLDFETFKEKKYRVCSIYWQQMVH--ISDTPN-FKLIGGTPYIYESLLDCRFRVS 349

  Fly   389 PLAFFQINTEGANVLY-------------------------QKAIDLVA--------------PT 414
            |.||||.|::.|.|||                         :||.:..|              |.
 Worm   350 PPAFFQTNSQAAAVLYSTIGEHCGLSEKKTNEDVPVETDASEKAPEAPAAPSEPIPDDPSDAPPA 414

  Fly   415 K--------------------DTTMLDICCGTGTITLAFAKHCKK-----VMGVEIVPDAIKDAE 454
            |                    .|.:||||||||||.....|:.:|     .:|:|::.:|::||:
 Worm   415 KIPRIEPEPTAADEAPAPEDPGTILLDICCGTGTIGQCLLKNIQKSQKVCCIGIEMIAEAVEDAK 479

  Fly   455 FNAEANGIKN-AKFFTGNADDFIKSMVREAL---YDQEPGKPLDLIAVVDPPRAGLHHRSIAAIR 515
            .||:.|.::. .|:..|.|:|..:|| |..|   :|....:   ::.|:||||||:|.:.|.|.|
 Worm   480 QNAKQNKMETCCKYIAGKAEDTFRSM-RYHLPNGFDLRKSR---VVGVLDPPRAGMHEKVILACR 540

  Fly   516 SADAINRLVYVSCNPHSAKRNFIELARPESKQYKGEPFYPKSAVAVDMFPHTMHTELVILFER 578
            ..:.:.||::|||.|::|..|.:.|.||.|::|.|:.|.......|||||.|.|.|.:|..:|
 Worm   541 EMETMRRLIFVSCEPNAAISNIVNLCRPSSRKYTGDAFSVTRVQPVDMFPQTNHMEWIIQLDR 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3808	NP_649083.2	RRM_TRMT2A	56..134	CDD:240885	25/78 (32%)
		TrmA	57..571	CDD:225174	177/592 (30%)
		AdoMet_MTases	276..579	CDD:302624	109/373 (29%)
trm-2A	NP_503353.2	RRM_TRMT2A	25..100	CDD:240885	25/78 (32%)
		TrmA	128..596	CDD:225174	142/481 (30%)
		SucB_Actino	<374..>437	CDD:200219	5/62 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156194
Domainoid	1	1.000	120	1.000	Domainoid score	I3581
eggNOG	1	0.900	-	-		E1_COG2265
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7374
Inparanoid	1	1.050	273	1.000	Inparanoid score	I1808
Isobase	1	0.950	-	0	Normalized mean entropy	S4977
OMA	1	1.010	-	-		QHG54357
OrthoDB	1	1.010	-	-		D248059at2759
OrthoFinder	1	1.000	-	-		FOG0001356
OrthoInspector	1	1.000	-	-		oto18252
orthoMCL	1	0.900	-	-		OOG6_100839
Panther	1	1.100	-	-	LDO	PTHR45904
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1692
SonicParanoid	1	1.000	-	-		X4037
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790