DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18135 and GDPD5

DIOPT Version :9

Sequence 1:	NP_788526.1	Gene:	CG18135 / 40073	FlyBaseID:	FBgn0036837	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	XP_011543578.1	Gene:	GDPD5 / 81544	HGNCID:	28804	Length:	606	Species:	Homo sapiens

Alignment Length:	162	Identity:	42/162 - (25%)
Similarity:	70/162 - (43%)	Gaps:	38/162 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 PKSWPNLDVGHRGNGKSYIADAP-AERENTIASFLSAHEHHADMIELDVHLTADGVPVIYHDFGL 511
            ||  |.| :||||        || ...|:|:.||..|.|.....::.|:.::.||||.:.||..|
Human   226 PK--PAL-IGHRG--------APMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTL 279

  Fly   512 RTAPPGKQ-----ISRPDQLEYVLIKDINYELLKRLRIFSVIAGQ--VREYP-------SHNAEP 562
            |.....::     ..||..:       :|:..|:||.     |||  ::..|       |.:...
Human   280 RRTTNVEEEFPELARRPASM-------LNWTTLQRLN-----AGQWFLKTDPFWTASSLSPSDHR 332

  Fly   563 RMEHRIFPTLVEVLEKLPKSLGIDVEIKWPQR 594
            ..:::...:|.|:||....:..:.:.::.|.|
Human   333 EAQNQSICSLAELLELAKGNATLLLNLRDPPR 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18135	NP_788526.1	CBM20_Prei4	166..288	CDD:99888
		GDPD_GDE5	454..741	CDD:176549	39/156 (25%)
		GDPD	458..744	CDD:281062	37/152 (24%)
GDPD5	XP_011543578.1	GDPD_GDE2	227..577	CDD:176550	41/161 (25%)
GDPD5	XP_011543578.1	UgpQ	227..468	CDD:223657	41/161 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900