DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18135 and gdpd3b

DIOPT Version :9

Sequence 1:	NP_788526.1	Gene:	CG18135 / 40073	FlyBaseID:	FBgn0036837	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	XP_017213986.2	Gene:	gdpd3b / 567286	ZFINID:	ZDB-GENE-121210-2	Length:	320	Species:	Danio rerio

Alignment Length:	239	Identity:	60/239 - (25%)
Similarity:	97/239 - (40%)	Gaps:	62/239 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 TLARLRLPYVAVQPYRYSPLDFKNTYAHYWPKSWPNLDVGHRGNGKSYIADAPAERENTIASFLS 482
            :|..||.|.:.   ::...|:|   |..:         :.|||.....|       |||:.:|..
Zfish    21 SLFLLRYPLIL---HKRKRLEF---YCRH---------ISHRGGSGERI-------ENTMEAFTH 63

  Fly   483 AHEHHADMIELDVHLTADGVPVIYHDFG-LRTAPPGKQISRPDQLEYVLIKDIN-YELLKRLRIF 545
            |.....||:|:|.|||.||..|:.||.. ||.....|.:|   .|::   :|:. ||  ::|
Zfish    64 AVSAGTDMLEMDCHLTLDGYVVVSHDNNLLRQTGDDKTVS---SLKF---QDLPLYE--EKL--- 117

  Fly   546 SVIAGQVREYPSHNAEPRMEHRIFPTLVEVLEKLPKSLGIDVEIKWPQRRQGGGSEAEQTIDKNF 610
                 :|..|..|.:..:  .|.|..|..||:..| ::.:.:|||                :.|.
Zfish   118 -----EVTFYVGHYSTGK--DRRFVLLENVLKNFP-NMPMTLEIK----------------ENND 158

  Fly   611 FADKVIHQVIQK-GCGRPIIFSSFDADMCTMLRFKQN-VFPVMF 652
            ...|.:..::.| |.....:::|.:.::.... .||| ..|.||
Zfish   159 LLIKKVSNLVHKYGREHITVWASEEHEVMAKC-LKQNPSMPYMF 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18135	NP_788526.1	CBM20_Prei4	166..288	CDD:99888
		GDPD_GDE5	454..741	CDD:176549	53/203 (26%)
		GDPD	458..744	CDD:281062	53/199 (27%)
gdpd3b	XP_017213986.2	GDPD_GDE4	17..312	CDD:176553	60/239 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810