DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18135 and GDPD2

DIOPT Version :9

Sequence 1:	NP_788526.1	Gene:	CG18135 / 40073	FlyBaseID:	FBgn0036837	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	NP_001164663.1	Gene:	GDPD2 / 54857	HGNCID:	25974	Length:	590	Species:	Homo sapiens

Alignment Length:	256	Identity:	64/256 - (25%)
Similarity:	100/256 - (39%)	Gaps:	62/256 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 PKSWPNLDVGHRGNGKSYIADAP-AERENTIASFLSAHEHHADMIELDVHLTADGVPVIYHDFGL 511
            ||  |.| |||||        || ...|||:.|.....|..|.:.|.||.:::||||.:.||
Human   222 PK--PGL-VGHRG--------APMLAPENTLMSLRKTAECGATVFETDVMVSSDGVPFLMHD--- 272

  Fly   512 RTAPPGKQISRPDQLEYVL-------IKDINYELLKRLRIFSVIAGQ--VREYPSHNAEP----- 562
                  :.:||...:..|.       ..|.::..||||.     ||.  :...|...|:|
Human   273 ------EHLSRTTNVASVFPTRITAHSSDFSWTELKRLN-----AGSWFLERRPFWGAKPLAGPD 326

  Fly   563 --RMEHRIFPTLVEVLEKLPKSLGIDVEIKWPQRRQGGGSEAEQTIDKNFFADKVIHQVIQKGCG 625
              ..|.:..|.|.|:||   ::..:::.|.:..||.........|     |..:.:..|:.....
Human   327 QKEAESQTVPALEELLE---EAAALNLSIMFDLRRPPQNHTYYDT-----FVIQTLETVLNARVP 383

  Fly   626 RPIIFSSFDADMCTMLRFKQNVFPVMFLTQG--ETKKWQ---------PFLDLRTRTFIAA 675
            :.::|...|.|...:.|....:..: :..||  .|::.|         |.||::.|..:.|
Human   384 QAMVFWLPDEDRANVQRRAPGMRQI-YGRQGGNRTERPQFLNLPYQDLPLLDIKDRFLLPA 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18135	NP_788526.1	CBM20_Prei4	166..288	CDD:99888
		GDPD_GDE5	454..741	CDD:176549	61/250 (24%)
		GDPD	458..744	CDD:281062	58/246 (24%)
GDPD2	NP_001164663.1	PI-PLCc_GDPD_SF	202..563	CDD:326331	64/256 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900