DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18135 and GDPD1

DIOPT Version :9

Sequence 1:	NP_788526.1	Gene:	CG18135 / 40073	FlyBaseID:	FBgn0036837	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	NP_872375.2	Gene:	GDPD1 / 284161	HGNCID:	20883	Length:	314	Species:	Homo sapiens

Alignment Length:	311	Identity:	72/311 - (23%)
Similarity:	114/311 - (36%)	Gaps:	115/311 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   456 VGHRGNGKSYIADAPAERENTIASFLSAHEHHADMIELDVHLTADGVPVIYHDFGLRTAPPGKQI 520
            :.|||.       |....|||:|:|..|.:...||:|||.|:|.|...|:.||..|:.| .|..:
Human    43 ISHRGG-------AGENLENTMAAFQHAVKIGTDMLELDCHITKDEQVVVSHDENLKRA-TGVNV 99

  Fly   521 SRPDQLEYVLIKDINY-EL---LKRLRIFSVIAGQVREYPSHNAEPRMEHRIFPTLVEVLEKLPK 581
            :         |.|:.| ||   |.:|.:....|.|..         ..::|| |.|.||.|..|.
Human   100 N---------ISDLKYCELPPYLGKLDVSFQRACQCE---------GKDNRI-PLLKEVFEAFPN 145

  Fly   582 SLGIDVEIKWPQRRQGGGSEAEQTIDKNFFADKVI------------------HQVIQKGCGR-- 626
            : .|:::||               ::.|....||.                  :::::| |.:
Human   146 T-PINIDIK---------------VNNNVLIKKVSELVKRYNREHLTVWGNANYEIVEK-CYKEN 193

  Fly   627 ---PIIFS---------SFDADMCTMLRFKQNVF----PVMFL------TQGETKKWQPFL-DL- 667
               ||:||         .|...:...:..::..|    |.:.|      |...::|:..:| ||
Human   194 SDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKEPHTMSRSQKFLIWLSDLL 258

  Fly   668 -------------RTRTFIAAVNNAQ----AFELAGTAPHAE------DFL 695
                         ..:.:|..:|..|    ||:|..|....:      |||
Human   259 LMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTDYPTKLRDFL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18135	NP_788526.1	CBM20_Prei4	166..288	CDD:99888
		GDPD_GDE5	454..741	CDD:176549	72/311 (23%)
		GDPD	458..744	CDD:281062	72/309 (23%)
GDPD1	NP_872375.2	GDPD_GDE4	14..311	CDD:176553	72/311 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810