DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18135 and gde1

DIOPT Version :9

Sequence 1:NP_788526.1 Gene:CG18135 / 40073 FlyBaseID:FBgn0036837 Length:770 Species:Drosophila melanogaster
Sequence 2:NP_594131.1 Gene:gde1 / 2543677 PomBaseID:SPAPB1E7.05 Length:1076 Species:Schizosaccharomyces pombe


Alignment Length:750 Identity:184/750 - (24%)
Similarity:296/750 - (39%) Gaps:207/750 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 LHSNPMAM----SRTVLILAVALSLQ---CAAFVDGASITYGTGNELESGSGSSAACKPTLREF- 173
            |.:||.|.    |.|.|:||.|..|.   ......|||:     :|::| ||.:|..:..:|.: 
pombe   389 LGANPSARDFLNSWTPLMLASATGLSEIVSILVASGASV-----DEVDS-SGWTAMEQAVVRGYL 447

  Fly   174 ----NVRLEVPLAAEERLGL-TGDVKALG----------EWQLSRSVALESLDELNWQATVALQS 223
                .:|.:|.| :::.:.| |..:||..          :.||||||.:..:.:|..:..|:||.
pombe   448 HLADKLRTQVAL-SDKPVNLHTLYIKASSSEMRSRKRAMDLQLSRSVVIIRISDLAGRIRVSLQG 511

  Fly   224 CRQLEYRYFVYVEDLS-GYKQIRRWETHFKPRSLGPCTELQCSQLDVFGITSDNSDLKPQVHRGW 287
            ...      |||...| .:...|.....|..:|        ...|.....|:.|..:.|...:  
pombe   512 DDA------VYVSGRSPSFAASRPSSVDFMSQS--------TDSLSKNDTTASNGSMTPSSSQ-- 560

  Fly   288 LNHEAILQLKFN-----GEKMFQVHDIETFDPQHVQLKIVPVEKTAGLHVEYSKQEYGKSQLELQ 347
             |:..|:.:..:     ||...:    ...:|..:      .:.:..||.:.:::.      ..|
pombe   561 -NNSVIIDIPRSHFDNAGEVCLE----NLAEPDEI------ADDSIHLHYDAAQEN------SPQ 608

  Fly   348 PTFG--VPYTKGDIVIF------HITLPLERMMEQHFRLECYSMSNELLGSATLVTSDLTGSEG- 403
            |..|  .||.    ::|      ..|:.::.:..:         |:::||......:.|....| 
pombe   609 PVNGSSPPYE----LVFVTRNTEEATITIDLLANR---------SHKILGRTVCCLTSLVSDLGN 660

  Fly   404 -------VLHLPIKSAK--------NADETLARL---------------RLPYVAVQPYRYSPLD 438
                   :..||:.|:|        |||..::::               .|...||.....:.|:
pombe   661 HMQSLKPLAPLPLLSSKTLKPIAHVNADVLISKVTVDDRFSSNDGISTPALSLEAVSNVSRTALE 725

  Fly   439 FKNTYAHYWPKSWPNLD----------VGHRGNGKSYIADAPAER------ENTIASFLSAHEHH 487
            ......|   ||.....          :||||.||:     ..:|      |||:.||:.|.:..
pombe   726 DAERSLH---KSATTTSESGKSNGVAVIGHRGLGKN-----QPDRLSLQLGENTLQSFIKAADLG 782

  Fly   488 ADMIELDVHLTADGVPVIYHDFGLRTAPPGKQISRPDQLEYVL---------IKDINYELLKRLR 543
            |..:||||.:|.|.|||:||||.:.......|: ....||..|         |||...::.::.|
pombe   783 ASYVELDVQMTKDMVPVVYHDFIVNETGTDAQV-HSLTLEQFLGASHSPSEEIKDDASDIQQKRR 846

  Fly   544 ------IFSVIAGQVR--EYPSHNA--EPR------MEHRI---FPTLVEVLEKLPKSLGIDVEI 589
                  .|:....||.  |:...||  :|:      :.|.|   |.||.:||:::|:|:|::||.
pombe   847 PRAYSSSFTPSGSQVNFGEFAEENARLKPKVYKGNALGHTICAPFTTLKDVLKEVPQSVGLNVEF 911

  Fly   590 KWPQRRQGGGSEAEQ------TIDKNFFADKVIHQVIQKGCGRPIIFSSFDADMCTMLRFKQNVF 648
            |:|..     ||||:      ..|.||:.|.::..:.:.|..|..|||||:.|:|.:|..| :..
pombe   912 KYPML-----SEAEEEKLLPIAYDYNFYVDTILSIIKKYGGKRKYIFSSFNPDICILLSLK-STN 970

  Fly   649 PVMFLTQGETKKWQPFLDLRTRTFIAAVNNAQAFELAGTAPHAEDFLG-ENASE-------MLRK 705
            ||:|||:|.|         ..||.:.|.:..||.:.|.    ...||| .:|.|       :::.
pombe   971 PVLFLTEGGT---------AYRTDVRAASLRQALKFAS----QWSFLGIVSACEPLIMCPRLIKA 1022

  Fly   706 AKDLGQIAVIWGDDCNSKERVQYFTRIGATATCYD 740
            .|.||.....:|...|..:.|:...|.|..|...|
pombe  1023 VKQLGLSCYTYGVLNNDVDNVRRQVRFGVDAVIVD 1057

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18135NP_788526.1 CBM20_Prei4 166..288 CDD:99888 29/138 (21%)
GDPD_GDE5 454..741 CDD:176549 102/344 (30%)
GDPD 458..744 CDD:281062 101/330 (31%)
gde1NP_594131.1 SPX <1..84 CDD:269894
ANK repeat 298..323 CDD:293786
ANK 336..453 CDD:238125 20/69 (29%)
ANK repeat 336..364 CDD:293786
Ank_2 337..431 CDD:289560 15/46 (33%)
ANK repeat 366..397 CDD:293786 4/7 (57%)
ANK repeat 399..431 CDD:293786 11/36 (31%)
GDPD_YPL110cp_fungi 746..1068 CDD:176548 102/336 (30%)
GDPD 752..1059 CDD:281062 101/330 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 133 1.000 Domainoid score I1291
eggNOG 1 0.900 - - E1_COG0584
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001717
OrthoInspector 1 1.000 - - otm46993
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22958
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X1268
TreeFam 1 0.960 - -
87.870

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