Protein Alignment CG18135 and gpcp-2

DIOPT Version :10

• Sequence 1: NP_788526.1
• Gene: CG18135 / 40073
• FlyBaseID: FBgn0036837
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001022321.1
• Gene: gpcp-2 / 174296
• WormBaseID: WBGene00011511
• Length: 796
• Species: Caenorhabditis elegans
• Alignment Length: 768
• Identity: 202/768 - (26%)
• Similarity: 345/768 - (44%)
• Gaps: 143/768 - (18%)

  Fly    59 RELGSRDSRQS-TPRLEKLYQAETESARGHRLISLAQQESCRAFNSGLRRSID---FQSARDLHS 119
            |.:|:.:|..| .||:.:..:.|.|...|..|....:|.        ::.:|.   .:...|.:.
 Worm    18 RHVGTINSSLSRRPRISECVEEEEEDGGGFDLFEEMRQP--------IQENIPMIILEEEEDDND 74

  Fly   120 NPMAMSRTVLILAVALSLQCAAFVDGASITYGTGNELESGSGSSAACKPTLREFNVRLEVPLAAE 184
            |        |:::||                                :|....|.|.:| .|.|.
 Worm    75 N--------LVMSVA--------------------------------RPVRVHFAVDVE-NLHAH 98

  Fly   185 ERLGLTGDVKALGEWQLSRSVAL-ESLDE-LNWQATVALQSCRQLEYRYFVYVEDLSGYKQ---I 244
            :.:.:.|....||.|:.:|::.| :..|. :.|:.:: :....||::|||:....:|...:   :
 Worm    99 QSVYVVGSNDVLGTWEATRAMPLVQDPDRFMRWKGSI-VTDVHQLKFRYFIGYNLMSDQGERLIV 162

  Fly   245 RRWETHFKPRS---LGPCTELQC--SQLDVFGITSDNSDLKPQVHRGWLNH----EAILQLKFNG 300
            .:||....|||   |......:|  .::|:||..:.    :..|..|||.:    :.:|:|..|.
 Worm   163 DKWEAFLHPRSTLCLAESRNDECRVDRVDLFGYYAG----RKCVSDGWLQYPDENQILLRLHGNA 223

  Fly   301 EKMFQVHDIETFDPQHVQLKIVPVE-----KTAGLHVEYSKQEYGKSQLELQPTFGVPYTKGDIV 360
            .|.::.    ..:.::.::|:.|::     ..:| |:.:|   ||:.:.:.:....||..|....
 Worm   224 LKFYKT----AKERKNCRVKMTPLDVRFKAPPSG-HISFS---YGEDEEDEEEDQNVPSNKCTHS 280

  Fly   361 IFHITL---PLERMMEQH--------------------------FRLECYSMSNELLGSATLVTS 396
            ..|:.:   |..:..:|.                          |.:|.:|...:.:|:...:.|
 Worm   281 ATHVAVLSDPRPKFYDQEDTGVTFNNNKDYLVFRTHCLAAEFLAFYIEIFSEERKRIGACYALPS 345

  Fly   397 DLTGSEGVLHLPIKSAKNADETLARLRLPYVAVQPYRY--SPLDFKNTYAHYWPKSWPNLDVGHR 459
            .|..:.|::|||.  ..::...:.::.:.|:.|:....  .|.....||..:|.|. ..|:||||
 Worm   346 SLQDASGIIHLPF--INSSGRPIGQVSIEYLCVRALTRLDGPQFMDQTYCRHWKKR-NALEVGHR 407

  Fly   460 GNGKSYIADAPAERENTIASFLSAHEHHADMIELDVHLTADGVPVIYHDF----------GLRTA 514
            |.|.||...|.| |||||.|..:|.::.||.:|.||.||.|.:.||||||          ||...
 Worm   408 GAGNSYTKFAMA-RENTIHSLNTAAKNGADYVEFDVQLTKDRIAVIYHDFHVLVSVARRDGLAMP 471

  Fly   515 PP--GKQISRPDQLEY--VLIKDINYELLKRLRIFSVIAGQVREYPS---HNAEPRMEHRIFPTL 572
            ||  .:|:. ...|:|  :.:||:....||.|.:..:...|.:|...   ...|...:.:.||||
 Worm   472 PPMTREQLD-SSNLDYHELPVKDLKLSQLKLLMLDHLSFPQKKENVKKLVEAGEEEEDFKPFPTL 535

  Fly   573 VEVLEKLPKSLGIDVEIKWPQRRQGGGSEAEQTIDKNFFADKVIHQVIQKGCGRPIIFSSFDADM 637
            :|.|.|:...:|.:||:|:|..:..|..|.:...::|.|.|.::..|::....|.|:|||||.|:
 Worm   536 LEALTKVDPDVGFNVEVKYPMMQNNGEHECDHYFERNLFVDVILADVMKHAGNRRIMFSSFDPDI 600

  Fly   638 CTMLRFKQNVFPVMFLTQGETKKWQPFLDLRTRTFIAAVNNAQAFELAGTAPHAEDFLGENASEM 702
            |:|:..|||.:||:||..|||:::.||.|.||.|.:.|||.|...:|.|...::||.|.:...
 Worm   601 CSMVATKQNKYPVLFLCVGETQRYTPFQDQRTSTSMTAVNFAAGADLLGVNFNSEDLLKDPMP-- 663

  Fly   703 LRKAKDLGQIAVIWGDDCNSKERVQYFTR-IGATATCYDRSDLFMPEGKREAF 754
            ::||.:.|.:..:||:|.:.||.:.||.: :|.....|||  :...|.:|..|
 Worm   664 VKKANEFGMVTFVWGEDLDKKENINYFKKELGVDGVIYDR--IGEEERRRNVF 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18135	NP_788526.1	CBM20_Prei4	166..288	CDD:99888	32/131 (24%)
		GDPD_GDE5	454..741	CDD:176549	112/304 (37%)
gpcp-2	NP_001022321.1	CBM20_Prei4	84..207	CDD:99888	31/128 (24%)
		GDPD_GDE5	402..704	CDD:176549	114/307 (37%)