Protein Alignment CG11619 and Gdpd4

DIOPT Version :10

• Sequence 1: NP_649081.1
• Gene: CG11619 / 40072
• FlyBaseID: FBgn0036836
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: XP_006507674.1
• Gene: Gdpd4 / 233537
• MGIID: 3606573
• Length: 730
• Species: Mus musculus
• Alignment Length: 744
• Identity: 133/744 - (17%)
• Similarity: 241/744 - (32%)
• Gaps: 298/744 - (40%)

  Fly   121 KWYLRVW-------ICAS--QRFYYRYLIYSKNRQGNRVLRTWEGQRVARMLQT----------- 165
            :|..|.|       .|.|  ::|:|..|:                  :|.:|..
Mouse    43 QWQYREWEKTELGSCCCSRKEQFFYMCLV------------------IAFILSVLFLFVWVETSN 89

  Fly   166 ------YEIYRSPGLDIFGEAYPVSVGG------------GFYLERGWLQYEYVIE--------- 203
                  :.:|...|...|.....:|..|            ||.|.  |.:.|..:.
Mouse    90 EYNGFDWVVYLGTGCWFFWSILVLSAAGIMVAYTTLLLLLGFLLL--WERIELNLHTSHKVFICL 152

  Fly   204 -----------LKFVWQDHIAISGMG----------SNAKYRLILT-PLNLID---DTRIEVSRY 243
                       |...|:|...|:|:.          |.....:|:: ||::..   ::.::|.|
Mouse   153 VIVLCSFLLAVLSHFWKDKWLIAGLSLQIFAPFVHLSLITVMIIISWPLSICVARLESEVKVRR- 216

  Fly   244 AYNQSSFRPQNQRGVRYTQGTIVVFRIYQPLDTYNALRLSIYQASRDLQLSLGEA--------YI 300
             |..:.:..:.|.                        |.:::|..|.||::.|.:        |:
Mouse   217 -YRMADYEQEIQE------------------------RCNVFQRLRALQIAAGLSFLIILLCLYL 256

  Fly   301 FPDQIKGSRGILQLPIFASLQNLAIGEITLPYLVVQPMPKVEAGNLRASFHHYWPDNWPTLDVGY 365
            .|      .||.. |.....:||.              ||                  ||| .|:
Mouse   257 MP------LGIYS-PCILKKENLG--------------PK------------------PTL-FGH 281

  Fly   366 RGLGASYFQSSTSLTENTIESYLAVLKAKGDMVQLDVQLTKDYVPVVWHGFGFYTSDTDRSV--- 427
            ||       :.....|||:.|:...::.....::.|:.|:.|.||.:.|.:....:...:.|
Mouse   282 RG-------APMLAPENTMMSFEKAVELDVSGLETDIYLSFDSVPFLMHDYDLTRTTNIKEVLPS 339

  Fly   428 -----RDRFDLRFVLIRELTYSELKASRVFILKRWTVQEYTNLNVKDVSQ--KHRI----FPKLS 481
                 ...|:..|:       |.|.|.      :|.::......:|.:|:  |.|.    .|:||
Mouse   340 AAGNHTSNFNWTFL-------STLNAG------KWFLKHKPFFGMKPLSEADKRRAGNQSIPQLS 391

  Fly   482 EVFEALPKTLGLLV--EIKWPQIMASGVPESTQSLNKNIYVDRILQITIHHGCGRPLIF--ASFD 542
            |:. ||.|....:|  ::..|:   .|.|      .:|.:|.|::::.:.....:.|||  ..||
Mouse   392 ELL-ALAKREQKIVIFDLFGPR---PGHP------LRNTFVRRVVKVILDSKIEQRLIFWLPGFD 446

  Fly   543 ADICTMIRLK----QHV-----------FPVILMSIGKSQIWDEYMDLR---------------- 576
            .|   .:|..    |||           ..:.::::...:::  |..||
Mouse   447 RD---YVRFMAPGFQHVGRLWSIKDLTKHNITIINVDYKRLF--YAGLRDYKEAKIYIHVYVINE 506

  Fly   577 ----AQSFQQAINFV--QSAEILGTALHVENFQNK--HQQVNLALDLQQSLFL-------WGNDM 626
                :.::..:||.|  .:.|:|........|...  :..:.|.||:..::.:       |..::
Mouse   507 PWLFSLAWCSSINSVTTDNIELLNQLSRPLFFMTPGFYMFMWLFLDIASAVIIGFVFCYNWIKEI 571

  Fly   627 QDEHLLEQFRALDVTGLIYDHMDRVGPFAWKRSEFFRAPQLMELFGAQCVSS--------GNST- 682
            :.|..||...:.|:        :|:. ...::||..||..|.:...|:..:|        |:||
Mouse   572 KRERWLEAAASSDI--------ERIN-LPKEKSEIQRASHLPKQLPARIGTSPWTPEVHYGSSTS 627

  Fly   683 --------TIPGIK-------PAKPTIWP 696
                    |:..:|       |.|.|:.|
Mouse   628 REKKPPPQTVQSVKAPKKKSVPFKNTVKP 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11619	NP_649081.1	CBM20_Prei4	69..196	CDD:99888	18/112 (16%)
		GDPD_GDE5	361..648	CDD:176549	66/350 (19%)
Gdpd4	XP_006507674.1	PI-PLCc_GDPD_SF	254..567	CDD:472694	72/387 (19%)