Protein Alignment SIGLEC16 and Siglecg

DIOPT Version :9

• Sequence 1: NP_001335293.2
• Gene: SIGLEC16 / 400709
• HGNCID: 24851
• Length: 481
• Species: Homo sapiens
• Sequence 2: XP_006540923.1
• Gene: Siglecg / 243958
• MGIID: 2443630
• Length: 757
• Species: Mus musculus
• Alignment Length: 511
• Identity: 268/511 - (52%)
• Similarity: 314/511 - (61%)
• Gaps: 89/511 - (17%)

Human     1 MLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGW 65
            |.||..||..|..|...:..||.|||||.|...||||:.|.|:.|.|...|...:..|||||||.
Mouse     1 MSLLLFLLSFLLDGPQGQMESYFLQVQRIVKAQEGLCIFVPCSFSSPEGKWLNRSPLYGYWFKGI 65

Human    66 TSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 130
            ..|....||||||:.:.:|...|.||||.||..|.:|||:|:|.|..|...||||:|||.. |.|
Mouse    66 RKPSLSFPVATNNKDKVLEWEARGRFQLLGDISKKNCSLLIKDVQWGDSTNYFFRMERGFE-RFS 129

Human   131 FVNNLFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST 195
            |... |.|:|.|||||||::|||.||||:||||:|:|:|.|.:||||||||.|.|:|.:.:||.|
Mouse   130 FKEE-FRLQVEALTQKPDIFIPEVLEPGEPVTVVCLFSWTFNQCPAPSFSWMGDAVSFQESRPHT 193

Human   196 SHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVA----SL------------ELQGNV 244
            |::|||||.|..|.|||:|||.:||||  :|.|||||||||    ||            :|..|.
Mouse   194 SNYSVLSFIPGLQHHDTELTCQLDFSR--MSTQRTVRLRVAYAPRSLAISIFHDNVSVPDLHENP 256

Human   245 IYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE 309
            .:||||:||.|||||.|||||||||||||:|:|||.|.|.|.|||.|||..|:|||||.|||:||
Mouse   257 SHLEVQQGQSLRLLCTADSQPPATLSWVLEDQVLSWSSPVGSRTLALELPWVKAGDSGHYTCQAE 321

Human   310 NRLGSQQRALDLSV--QY----------------------------------------------- 325
            |||||||..|||||  :|
Mouse   322 NRLGSQQHTLDLSVLCEYDLPKVPGPKKDKGVTSGYKQSDYCAACVGDPMSDAPTHPQLPSLGGM 386

Human   326 --------------------PPENLRVMVSQANRTVLENLRNGTSLRVLEGQSLRLVCVTHSSPP 370
                                ||::|||.||||||||||.|||..||.|||||||.|||||:|:||
Mouse   387 FCPGRRPWPVWSQFPVFIADPPQDLRVTVSQANRTVLEILRNAISLPVLEGQSLCLVCVTYSNPP 451

Human   371 ARLSWTRWGQTVGPSQPSDPGVLELPRVQMEHEGEFTCHARHPLGSQRVSLSFSVH 426
            |.:||....||:.|.|.|:|||||||.||.||||||||.|::|||:||:|||.|||
Mouse   452 ANVSWAWVTQTLIPIQSSEPGVLELPLVQREHEGEFTCAAQNPLGAQRISLSLSVH 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIGLEC16	NP_001335293.2	Ig_Siglec_N	22..141	CDD:143189	58/118 (49%)
		IG_like	247..323	CDD:214653	58/75 (77%)
		IG_like	350..425	CDD:214653	51/74 (69%)
Siglecg	XP_006540923.1	Ig	22..132	CDD:386229	56/110 (51%)
		Ig	145..216	CDD:386229	45/70 (64%)
		Ig	256..335	CDD:386229	58/78 (74%)
		IG	431..506	CDD:214652	51/74 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	160	1.000	Domainoid score	I32006
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001383
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X34
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010