DRSC/TRiP Functional Genomics Resources

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Protein Alignment SIGLEC16 and LOC101884775

DIOPT Version :9

Sequence 1:NP_001335293.2 Gene:SIGLEC16 / 400709 HGNCID:24851 Length:481 Species:Homo sapiens
Sequence 2:XP_009298710.1 Gene:LOC101884775 / 101884775 -ID:- Length:509 Species:Danio rerio


Alignment Length:470 Identity:94/470 - (20%)
Similarity:160/470 - (34%) Gaps:147/470 - (31%)


- Green bases have known domain annotations that are detailed below.


Human    22 YSLQVQRQVPVPEGLCVIVSC----NLSYPRDGWDESTAAYGYWFKGWTSPKTGAPVATNNQSRE 82
            :::.:..::....|.||::.|    |.:|.:   |.:..|.|.|:|. |..|:.:||..::    
Zfish    22 FNISLPEKIQALSGSCVVIKCRFEINETYDK---DLTERAAGVWYKD-THDKSSSPVFNSS---- 78

Human    83 VEMSTRDRF---QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFVNNLFFLKVTALT 144
              .||::.|   .:||......|:.|..|........||||:|....::.:|..:...:.|....
Zfish    79 --ASTQNSFIKGNITGQLNYKDCTTVFYDVTSNHSGQYFFRIEGEGGLKWTFTKSNTSVVVIESP 141

Human   145 QKPDVYI----------PETLEPGQPVTVICVFNWAFKKCPAP--SFSWTGAALSPRRTRPSTSH 197
            ..|.|.:          .|.|| |:.|::.|.   |...|.:|  :.:|:..|..|.........
Zfish   142 VNPQVVLYVNEQELQDQQEVLE-GRSVSLRCS---ADDLCSSPPATLTWSSTARIPHSESSKLQE 202

Human   198 --FSVLSFTPSPQDHDTDLTCHVDFSRK--GVSAQRTVRLRVASLELQGNVIYLEVQKGQFLRLL 258
              .|.|:||.:.:.|....||.:.:..:  ..:|..::.|.|   :....::......|......
Zfish   203 LIISDLNFTAAQRHHRVTFTCSISYQLQDNNKTAHSSITLHV---QYAPQILNSSCNIGNVNVCF 264

Human   259 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQRALDLSV 323
            |..|..|...:.|.|..|::|:|                           .|...|::|..:.| 
Zfish   265 CEVDGNPSPVVEWHLSGRLVSNS---------------------------SNMFISEERLSNTS- 301

Human   324 QYPPENLRVMVSQANRTVLENLRNGTSLRVLEGQSLRLVCV---THSSPPARLSWTRWGQTVGPS 385
                                 ||:..||.....|:..|:||   ||.:...:|            
Zfish   302 ---------------------LRSFISLDQSLTQTSTLLCVSKNTHGNESLQL------------ 333

Human   386 QPSDPGVLELPRVQMEHEGEFTCHARHPLGSQRVSLSFSVHCKSGPMTGVVLVAVGEVAMKILLL 450
                     ||                  .|.|:|.||.       :.||.:|         ||:
Zfish   334 ---------LP------------------SSTRLSFSFM-------LIGVAVV---------LLV 355

Human   451 CLCLILLRVRSCRRK 465
            .|..:::.:|..|.|
Zfish   356 TLISVIIYLRKERGK 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SIGLEC16NP_001335293.2 Ig_Siglec_N 22..141 CDD:143189 29/125 (23%)
IG_like 247..323 CDD:214653 12/75 (16%)
IG_like 350..425 CDD:214653 16/77 (21%)
LOC101884775XP_009298710.1 Ig 22..137 CDD:299845 29/124 (23%)
Ig 154..230 CDD:299845 19/79 (24%)
IG_like 158..244 CDD:214653 21/89 (24%)
DUF499 276..>493 CDD:303008 36/199 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12035
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X34
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
44.010

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