DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3819 and NUC1

DIOPT Version :9

Sequence 1:	NP_001262027.1	Gene:	CG3819 / 40069	FlyBaseID:	FBgn0036833	Length:	423	Species:	Drosophila melanogaster
Sequence 2:	NP_012327.1	Gene:	NUC1 / 853222	SGDID:	S000003744	Length:	329	Species:	Saccharomyces cerevisiae

Alignment Length:	340	Identity:	74/340 - (21%)
Similarity:	129/340 - (37%)	Gaps:	71/340 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 CTSSLASPLSGKSVTAKCVGGTTFKIDDKEHDLSAIKCTSWPVFVGKKSGSSCNG------GTTL 151
            |:..|.|.|.|.....    |.|:.:.:| |..:.|..|.:|  ..:|..|:...      .:..
Yeast     2 CSRILLSGLVGLGAGT----GLTYLLLNK-HSPTQIIETPYP--PTQKPNSNIQSHSFNVDPSGF 59

  Fly   152 IKVGF--ELSGSRFATQYEVCFNEDEEVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDK 214
            .|.||  .:...:...::..|:|...:...:|...:.|.:                 .|.:|.|:
Yeast    60 FKYGFPGPIHDLQNREEFISCYNRQTQNPYWVLEHITPES-----------------LAARNADR 107

  Fly   215 LYTQAVQKETIDKELDMDSSRFFDSAKNIFLA---RGHMGAKADFVFAPEQRA---TFLFINAAP 273
                   |.:..||.::...:|....::.|.:   |||....||..|:  |:|   ||...|..|
Yeast   108 -------KNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFS--QQAMDDTFYLSNMCP 163

  Fly   274 Q-WQTFNAGNWARVEDGVRAWVAKENKHVECWTGVWGVTTLPNKNGEQRQLYLSHDNNGN-GLIP 336
            | .:.||...||.:|...|. :.|:.|.|..   |.|...||.|:....:..::::..|| ..|.
Yeast   164 QVGEGFNRDYWAHLEYFCRG-LTKKYKSVRI---VTGPLYLPKKDPIDNKFRVNYEVIGNPPSIA 224

  Fly   337 VPKLYFRVVI------EPSTKK-GIVLIGVNNPHLSLEEIKRDYILCTDVSDRINWISWKKTDIT 394
            ||..:|::::      .|:.:. .:....:.|..:|.|....|:.:..|..:|           :
Yeast   225 VPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALER-----------S 278

  Fly   395 AGYSYACEVPEFRKK 409
            .|.....:||..:||
Yeast   279 TGLELLQKVPPSKKK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3819	NP_001262027.1	NUC	164..415	CDD:238043	57/261 (22%)
NUC1	NP_012327.1	NUC1	8..308	CDD:224777	72/334 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010