DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3819 and CG14118

DIOPT Version :9

Sequence 1:	NP_001262027.1	Gene:	CG3819 / 40069	FlyBaseID:	FBgn0036833	Length:	423	Species:	Drosophila melanogaster
Sequence 2:	NP_648612.1	Gene:	CG14118 / 39465	FlyBaseID:	FBgn0036323	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	130/440 - (29%)
Similarity:	227/440 - (51%)	Gaps:	42/440 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLIAFSGLFLASAQARILPAEDLPWELPEVPVAVNEIE---------PRAAGCSIKIRSS--ELK 58
            :::.|.||.||....|.:.|.:....:|:|...:.:::         .:.:.|.:.:::.  .|.
  Fly     1 MMLQFIGLILAVVILREIRAREAIATIPDVGQIIKDLDGLHIDGEMFHQGSPCRVDVQNDLPRLD 65

  Fly    59 DPQPLLIKSDTSEIVGFSDTGYVDVDKDKTIEFHCTSSLASPLSGKSVTA-------KCVGGTTF 116
            ..|||.::..|......:..|:::|.:..:||.||:.|.| |.:|:|:.|       |||..|||
  Fly    66 KVQPLYLRPGTDLYWLPNAYGHLEVQRGASIELHCSHSFA-PANGESLDAKLRSIRVKCVQDTTF 129

  Fly   117 KIDDKEHDLSAIKCTSWPVFVGKKSGSSCNGGTT------LIKVGFELSGSRFATQYEVCFNEDE 175
            :....:...|...|.....:..::...||...|.      |.:||::....||....|:|.:.::
  Fly   130 EWMGAKIHFSDFVCNHSMPYTVERLDRSCGSDTPSPSTSYLYRVGYDTGDGRFVATMELCHDPNQ 194

  Fly   176 EVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSA 240
            ..|.|.:|:|.|.|.::...:.|..|...|:|.|.::.::|:...|::.:...|       .|..
  Fly   195 LRTHYAHHQLTPANVHFQKKLKRPRFSTAGHFTGFDMARIYSPKSQEKLMVPGL-------IDVK 252

  Fly   241 KNIFLARGHMGAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVAKENKHVECWT 305
            ..:||||||:.||||.::|.:|:::|.::|.|||||:||.|.|:::|:..|.:||:.......:|
  Fly   253 SGLFLARGHLTAKADLIYASQQKSSFNYMNVAPQWQSFNGGQWSKLEESTRQYVARSGITATVYT 317

  Fly   306 GVWGVTTLPNKNGEQRQLYLSHDNNGNGLIPVPKLYFRVVI-EPSTKKGIVLIGVNNPHLSLEEI 369
            |::|    ..|....:.|:::.:.|..|::.||:|::||:| |....:||.|:||||||.:|.:|
  Fly   318 GIYG----EMKVAGSKVLHMTTNANNIGVVAVPQLFYRVLIDEGHPTRGIALVGVNNPHATLAQI 378

  Fly   370 KRDYILCTDVSDRINWISW-----KKTDITAGYSYACEVPEFRKKVTHLP 414
            ...||:|..|.:.:.|:||     .|.::..||.|||.|....:.|.|||
  Fly   379 HESYIICDPVEESVQWLSWLHKSNAKGNLKNGYLYACSVANLARAVGHLP 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3819	NP_001262027.1	NUC	164..415	CDD:238043	87/257 (34%)
CG14118	NP_648612.1	NUC	175..428	CDD:238043	87/263 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2ANB2
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102209at6960
OrthoFinder	1	1.000	-	-		FOG0014393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850