DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18223 and CG18754

DIOPT Version :9

Sequence 1:	NP_649077.1	Gene:	CG18223 / 40068	FlyBaseID:	FBgn0036832	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	210	Identity:	54/210 - (25%)
Similarity:	88/210 - (41%)	Gaps:	25/210 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 YILTSAHCA----MDKRKIVHRSRVLVVVAGTTNRLKSRKGL-SLNMEVKKIFVPDKFTVFN--- 144
            |:||:|||.    :.:..:|.:|  :.:...||:.:.|.... .|::||.:..|...||...
  Fly   134 YVLTAAHCVIGGYLTQNDLVLKS--VRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTY 196

  Fly   145 TNNIALMMLAKKLPLDNPLVGVINLPTADPEPGLNYTVLGWGRIFKGGPLASDILHIDVELLPRD 209
            .|:|||:.|...:.....:..:..|....|...||..:.||........|.:..:.   |..|.|
  Fly   197 RNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQISGWDPTKSSQTLITSTVK---ERNPAD 258

  Fly   210 ICEKKVHIFKEEMMCAGNLNNTMDENPCAGDTGSPLI------FNETVF--GVVSY-RVGCGSKT 265
            ...:.........:|||....   .:.|||.:|||::      .:|.||  |:.|| :..|.|..
  Fly   259 CLNRYPSFRSASQVCAGGQRK---GDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAG 320

  Fly   266 LPSIYTNVYMHMDWI 280
            :|.:||.:....:||
  Fly   321 IPGVYTKIGHFSEWI 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18223	NP_649077.1	Tryp_SPc	60..283	CDD:238113	54/210 (26%)
CG18223	NP_649077.1	Tryp_SPc	60..280	CDD:214473	52/208 (25%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	54/210 (26%)
		Tryp_SPc	108..335	CDD:214473	52/208 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030