DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18223 and modSP

DIOPT Version :9

Sequence 1:	NP_649077.1	Gene:	CG18223 / 40068	FlyBaseID:	FBgn0036832	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	52/255 - (20%)
Similarity:	96/255 - (37%)	Gaps:	59/255 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 DNHF-CGGVIISRTYILTSAHCAMDK-RKIVHRSRVLVVVA-------GTTNRLKSRKGLSLNME 130
            |.|| |||.:::...::|:|||..|: .::.:......|:|       |.|...:.|:      :
  Fly   394 DYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRR------D 452

  Fly   131 VKKIFVPDKFTVFNTN---NIALMMLAKKLPLDNPL--VGVINLPTADPE---PGLNYTVLGWGR 187
            |:.|.:...:.....|   ::||:.|.:...|.:.:  :.|.....|:.|   ..:.....||..
  Fly   453 VRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNI 517

  Fly   188 IFKGGPLASDILHIDVELLP-----RDICEKKVHIFKEEMMCAGNLNNTMDENPCAGDTG----S 243
            ..|         | :::.:|     ..:|.:.:...:.:..|......::   .|.||:|    |
  Fly   518 ENK---------H-ELQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGKSL---ACQGDSGGGFTS 569

  Fly   244 PLIFN---------ETVFGVVSYRVG---CGSKTLPSIYTNVYMHMDWINGIMNNNEANR 291
            .|..|         ..:|||:|....   |....  ::.||:....|.|...||.:...|
  Fly   570 ELPTNAFSTWNTARHFLFGVISNAPNADQCAHSL--TVMTNIQHFEDMILNAMNRSVETR 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18223	NP_649077.1	Tryp_SPc	60..283	CDD:238113	49/245 (20%)
CG18223	NP_649077.1	Tryp_SPc	60..280	CDD:214473	48/242 (20%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	48/242 (20%)
		Tryp_SPc	371..591	CDD:304450	43/215 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030