DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18223 and spirit

DIOPT Version :9

Sequence 1:	NP_649077.1	Gene:	CG18223 / 40068	FlyBaseID:	FBgn0036832	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	66/253 - (26%)
Similarity:	112/253 - (44%)	Gaps:	61/253 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 CGGVIISRTYILTSAHCAMDKRKIVHRSRVLVVVAGTTNRLKSRKGLSLNMEVKKIFVPDKFTVF 143
            |||.:|:..::||:||||    .:.......|.:.|....|...:.:|:.   :.|..||.....
  Fly   163 CGGALIANNFVLTAAHCA----DLGGEPPSQVRLGGDNLTLTEGEDISIR---RVIIHPDYSAST 220

  Fly   144 NTNNIALMML---AK----------KLPLDNPLVGVINLPTADPEPGLNYTVLGWGRIFKGGPLA 195
            ..|:|||:.|   ||          :..:.|.||                |.:|:|:....|..:
  Fly   221 AYNDIALLELETAAKPELKPTCIWTQKEVTNTLV----------------TAIGYGQTSFAGLSS 269

  Fly   196 SDILHIDVELLPRDICEKKVHIFKEEM--------MCAGNLNNTMDENPCAGDTGSPLIFNE--- 249
            :.:|.:.::.:..:.|:.  |..|:::        ||||::  |.:.:.|.||:|.||:..:
  Fly   270 AQLLKVPLKSVSNEECQH--HYQKDQLAQGVLGTQMCAGDI--TGERDTCQGDSGGPLLMQDGLL 330

  Fly   250 -TVFGVVSYRVGCGSKTLPSIYTNVYMHMDWINGIM-------NNNEANRL-CYSPNY 298
             .|.|:.|...||.|.. ||:||.|...:|||.||:       |..:.|:: .:||.:
  Fly   331 GYVVGITSLGQGCASGP-PSVYTRVSSFVDWIEGIVWPAQQVTNAPQPNQMTSFSPEF 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18223	NP_649077.1	Tryp_SPc	60..283	CDD:238113	60/228 (26%)
CG18223	NP_649077.1	Tryp_SPc	60..280	CDD:214473	58/225 (26%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	60/228 (26%)
		Tryp_SPc	132..361	CDD:214473	58/225 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940