DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18223 and CG30091

DIOPT Version :9

Sequence 1:	NP_649077.1	Gene:	CG18223 / 40068	FlyBaseID:	FBgn0036832	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	311	Identity:	75/311 - (24%)
Similarity:	130/311 - (41%)	Gaps:	67/311 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LDAGDPIGSHFVRRRAKRLSSPYFDKEKTLVLAKYVVSIRSRRPHKLFGDNHFCGGVIISRTYIL 90
            :|||:             |.:|:....||                   .|...|||.:|:..::|
  Fly    41 VDAGE-------------LKNPWMALIKT-------------------NDEFICGGSVITNKFVL 73

  Fly    91 TSAHCAMDKRKIVHRSRVLVVVAGTTNRLKSRKGLSLN--MEVKKIFVPDKFTVFN-TNNIALMM 152
            |:|||.....:.:.:...|.|..|..:.|.:.:....:  ..|:::::.|.|.:.| .|:|||:.
  Fly    74 TAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLR 138

  Fly   153 LAKKL---PLDNPLVGVINLPTADPEPGL--NYTVLGWGRIFKGGPLASDILHIDVELLPRDICE 212
            |.|.:   |...||..::| ....|:..|  .:|.:||| :...|.:::::..:.:..:.|.:||
  Fly   139 LQKSIVYKPQIKPLCILLN-DQLKPQTDLIQEFTAIGWG-VTGNGKMSNNLQMVKIYRIDRKMCE 201

  Fly   213 KKV-HIFKEEMMCAGNLNNTMDENPCAGDTGSPL--------IFNETVFGVVSYRV----GCGSK 264
            ... :.|...|.|||   ..:..:.|..|:|.||        |...|..|:||...    |.|
  Fly   202 AAFWYTFDYPMFCAG---TAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGFG-- 261

  Fly   265 TLPSIYTNVYMHMDWINGIMNNNEANRLCYSPNYLFTTIGIIIGNKILKSW 315
                :||:|..|:|:|..|:.:.:...:.   .|:.......:||..|.||
  Fly   262 ----MYTDVMGHIDFIERIVLDADIEVVL---PYIDLLDAGCLGNDTLNSW 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18223	NP_649077.1	Tryp_SPc	60..283	CDD:238113	61/243 (25%)
CG18223	NP_649077.1	Tryp_SPc	60..280	CDD:214473	60/240 (25%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	67/274 (24%)
		Tryp_SPc	37..276	CDD:238113	68/277 (25%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030