DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir75d and GLR2.1

DIOPT Version :9

Sequence 1:	NP_649074.2	Gene:	Ir75d / 40065	FlyBaseID:	FBgn0036829	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_198062.2	Gene:	GLR2.1 / 832768	AraportID:	AT5G27100	Length:	901	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	96/493 - (19%)
Similarity:	163/493 - (33%)	Gaps:	152/493 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 KRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRHIDTISK 291
            ||..:|..:.|               |::|          .|.|..|..||....|...||....
plant   452 KRLQIGVPVNN---------------TFQQ----------FVKATRDPITNSTIFSGFSIDYFEA 491

  Fly   292 VNHRLMLELANRLNMSYNTYQTVNYGWRQPNGSFDGLMGRFQ----RYELDLAQLAIFMRLDRIA 352
            |...:..::         :|..:.:    .:|.:|.|:  :|    :|:..:|...|  ..:|..
plant   492 VIQAIPYDI---------SYDFIPF----QDGGYDALV--YQVYLGKYDAVVADTTI--SSNRSM 539

  Fly   353 LVDFVAETYRVRAGIMFRQPPLSAV---ANIFAMPFENDVW-VSILMLLIITTVVLVLEL----- 408
            .||| :..| ..:|:....|...:|   :.||.||....:| :|:|...||..||.|||.
plant   540 YVDF-SLPY-TPSGVGLVVPVKDSVRRSSTIFLMPLTLALWLISLLSFFIIGLVVWVLEHRVNPD 602

  Fly   409 FFSPHNHDMSYMDTLNFVWGAMCQQGFYVEVRNRS--ARIIVFTTFVAALFLFTSFSANIVALLQ 471
            |..|..:.:|     ...|.:.....|....|..|  ||::|...:...|.|..|::|::.:||.
plant   603 FDGPGQYQLS-----TIFWFSFSIMVFAPRERVLSFWARVVVIIWYFLVLVLTQSYTASLASLLT 662

  Fly   472 SPSDAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKM 536
                                           |:...|...|:  ..:.:|||::..:....:.::
plant   663 -------------------------------TQHLHPTVTNI--NSLLAKGESVGYQSSFILGRL 694

  Fly   537 RTGLFAYQVELQAGYQIVSDTFSEPEKCG---------------LMEL----------------- 569
            |...|:..       .:||  :..||.|.               |||:
plant   695 RDSGFSEA-------SLVS--YGSPEHCDALLSKGQAEGGVSAVLMEVPYVRIFLGQYCNKYKMV 750

  Fly   570 -EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWI-PQKPKCEGGVG--------G 624
             .||::..|........|....|.|.:....|.:..|:.|..|. |....|...:.        .
plant   751 QTPFKVDGLGFVFPIGSPLVADISRAILKVEESNKANQLENAWFKPIDESCPDPLTNPDPNPSVS 815

  Fly   625 FVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQ 662
            |..:|..    :..:....||:...:.|.:|:::..|:
plant   816 FRQLGFD----SFWVLFLVAAIVCTMALLKFVYQFLKE 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	46/198 (23%)
Ir75d	NP_649074.2	Lig_chan	388..644	CDD:278489	56/305 (18%)
GLR2.1	NP_198062.2	PBP1_GABAb_receptor	49..411	CDD:107361
		ANF_receptor	49..392	CDD:279440
		GluR_Plant	452..794	CDD:270404	86/432 (20%)
		Periplasmic_Binding_Protein_Type_2	478..>685	CDD:304360	56/263 (21%)
		Lig_chan	576..835	CDD:278489	58/309 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000