Protein Alignment Ir75d and GLR2.8

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001324459.1
• Gene: GLR2.8 / 817459
• AraportID: AT2G29110
• Length: 948
• Species: Arabidopsis thaliana
• Alignment Length: 683
• Identity: 137/683 - (20%)
• Similarity: 239/683 - (34%)
• Gaps: 181/683 - (26%)

  Fly    56 HHG-----VHSLMLVVCHT----DIADFRL-WKLWQHFNLNNFYVQVSTESSLRDLQHVD----- 105
            |||     :..::.|..|.    .:.|||| ||  ::|...|.:::  .:.|:..|...|
plant   266 HHGRSLNTIDGVLGVRSHVPKSKGLEDFRLRWK--RNFKKENPWLR--DDLSIFGLWAYDSTTAL 326

  Fly   106 --ALDEHKDAPPP---KSFHANNSTHWETSFLLPALPYKMGILLLEFSSECALNLLRWSAASEHN 165
              |:::...:..|   .|..:||.|...|..:     .:.|..|||..||...|.|
plant   327 AMAVEKTNISSFPYNNASGSSNNMTDLGTLHV-----SRYGPSLLEALSEIRFNGL--------- 377

  Fly   166 YFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTL 230
               ..||.|:..:       ||.|        :..::::  |||      :...|..|.| ...|
plant   378 ---AGRFNLIDRQ-------LESP--------KFEIINF--VGN------EERIVGFWTP-SNGL 415

  Fly   231 VGHNIRNSRHVIHALQHFGSAI---------------TYRQDLE-GI-----VFNSAIVIAFPDL 274
            |  |:.:::......:.||..|               |..:.:: |:     .||...||..|
plant   416 V--NVNSNKTTSFTGERFGPLIWPGKSTIVPKGWEIPTNGKKIKVGVPVKKGFFNFVEVITDP-- 476

  Fly   275 FTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTV--NYGWRQPNGSFDGLMGRFQRYEL 337
            .|||.......||.......:|             .|..:  .|.:..|:..:|.|:.:.....|
plant   477 ITNITTPKGYAIDIFEAALKKL-------------PYSVIPQYYRFESPDDDYDDLVYKVDNGTL 528

  Fly   338 DLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVAN----IFAMPFENDVWV-SILMLL 397
            |.....:.:...|....||..........:|.   |:....|    :|..|:..|:|| :....:
plant   529 DAVVGDVTITAYRSLYADFTLPYTESGVSMMV---PVRDNENKNTWVFLKPWGLDLWVTTACFFV 590

  Fly   398 IITTVVLVLEL-----FFSPHNHDMSYMDTLNFVWGAMCQQGF--YVEVRNRSARIIVFTTFVAA 455
            :|..||.:.|.     |..|.:|.:.     ...|.:.....|  ..:|.:..||.:|.......
plant   591 LIGFVVWLFEHRVNTDFRGPPHHQIG-----TSFWFSFSTMVFAHREKVVSNLARFVVVVWCFVV 650

  Fly   456 LFLFTSFSANIVALL--QSPSDAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTK------- 511
            |.|..|::||:.:.|  |....|..::.||.::...:|.|...:.|.:..:....|:|
plant   651 LVLTQSYTANLTSFLTVQRFQPAAINVKDLIKNGDYVGYQHGAFVKDFLIKEGFNVSKLKPFGSS 715

  Fly   512 -----NLYHKKIASKGENI-YMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELE 570
                 .|.:..|::..:.: |:|.:|.             :..:.|.||..||   :..|.
plant   716 EECHALLSNGSISAAFDEVAYLRAILS-------------QYCSKYAIVEPTF---KTAGF---- 760

  Fly   571 PFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVGGFVSIGITECRY 635
            .|..|       :|.|....:.:.:....:...:...|.||..::..|..     ....::..|.
plant   761 GFAFP-------RNSPLTGDVSKAILNVTQGDEMQHIENKWFMKQNDCPD-----PKTALSSNRL 813

  Fly   636 AL----GIF---GCGAAVSFVLFLFEFIF--RH 659
            :|    |:|   |..:.::.::|:|.|::  ||
plant   814 SLRSFWGLFLIAGIASFLALLIFVFLFLYENRH 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	11/74 (15%)
		Lig_chan	386..643	CDD:459656	55/286 (19%)
GLR2.8	NP_001324459.1	PBP1_GABAb_receptor_plant	35..419	CDD:380645	46/199 (23%)
		GluR_Plant	454..795	CDD:270404	75/390 (19%)