DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir75d and GLR2.2

DIOPT Version :9

Sequence 1:	NP_649074.2	Gene:	Ir75d / 40065	FlyBaseID:	FBgn0036829	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_180048.1	Gene:	GLR2.2 / 817008	AraportID:	AT2G24720	Length:	920	Species:	Arabidopsis thaliana

Alignment Length:	391	Identity:	85/391 - (21%)
Similarity:	135/391 - (34%)	Gaps:	112/391 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 YGWRQPNGSFDG---------LMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQ 371
            :.:.:|||...|         .:|:|.....|...||     :|.:.|||.....:...|::.
plant   505 FPFEKPNGEPAGNHNDLVHQVYLGQFDAVVGDTTILA-----NRSSFVDFTLPFMKSGVGLIV-- 562

  Fly   372 PPLSAVAN----IFAMPFENDVWVSILMLLIITTV-VLVLEL-----FFSPHNHDMSYMDTLNFV 426
             ||.....    .|..|...::|::.|:...:..: |..||.     |..|.|:..|     ...
plant   563 -PLKDEVKRDKFSFLKPLSIELWLTTLVFFFLVGISVWTLEHRVNSDFRGPANYQAS-----TIF 621

  Fly   427 WGAMCQQGFYVEVRNRS--ARIIVFTTFVAALFLFTSFSANIVALL--QSPSDAIQSLSDLGQSP 487
            |.|.....|....|..|  ||.:|.|.:...|.|..|::|::.:||  |..:..|.|:|.|....
plant   622 WFAFSTMVFAPRERVLSFGARSLVVTWYFVLLVLTQSYTASLASLLTSQQLNPTITSMSSLLHRG 686

  Fly   488 LEIGVQDTQY-----NKIYFTEST----------DPVTKNLYHKKIASKGENI--------YMRP 529
            ..:|.|.|.:     |:..|.:|:          |.:.|.      ..|...:        |:|.
plant   687 ETVGYQRTSFILGKLNETGFPQSSLVPFDTAEECDELLKK------GPKNGGVAAAFLGTPYVRL 745

  Fly   530 LLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFPYKELIRRQ 594
            .|| :...|            |::|.:.|:..   |...:.|...|::|..:|       .|.:.
plant   746 FLG-QYCNT------------YKMVEEPFNVD---GFGFVFPIGSPLVADVSR-------AILKV 787

  Fly   595 LRWQREVSLVNREERKWIPQKPK-C----------------EGGVGGF---VSIGITECRYALGI 639
            ....:.|.|    |..|..:|.: |                :.|||.|   ..:....|..|||.
plant   788 AESPKAVEL----EHAWFKKKEQSCPDPVTNPDSNPTVTAIQLGVGSFWFLFLVVFVVCVLALGK 848

  Fly   640 F 640
            |
plant   849 F 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	46/189 (24%)
Ir75d	NP_649074.2	Lig_chan	388..644	CDD:278489	67/306 (22%)
GLR2.2	NP_180048.1	PBP1_GABAb_receptor	33..412	CDD:107361
		ANF_receptor	47..392	CDD:279440
		HisJ	438..>587	CDD:223904	19/89 (21%)
		GluR_Plant	452..801	CDD:270404	73/341 (21%)
		Lig_chan	582..819	CDD:278489	58/274 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000