Protein Alignment Ir75d and grik5

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 661
• Identity: 148/661 - (22%)
• Similarity: 259/661 - (39%)
• Gaps: 162/661 - (24%)

  Fly    88 FYVQVSTESSLRDLQHVDALDEHKDAPPPKSFHANNSTHWETSFLLPALPYKMGILLLEFSSECA 152
            ||..:.|......|...|.:||..:.   ..|...|:||          |:     .|||..  :
Zfish   252 FYKYILTTMDFPLLWLDDIVDEQSNI---VGFSMFNTTH----------PF-----YLEFIR--S 296

  Fly   153 LNLLRWSAASEHNYFTTNRFWLLLTEDPG----DIDLLEDPEIFIPPDSELRVLHYENVGNFSC- 212
            || |.|....:.|.:            ||    ...|.:...:.:....||.......|...||
Zfish   297 LN-LSWREGCDINPY------------PGPALSSALLFDAVHVVVSAVQELNRSQEIGVKPLSCT 348

  Fly   213 ---------SLIDLYKVAAWKPLKRTLVGHNIRNSR--HVIHALQ-HFGSAITYRQDLEGIVF-N 264
                     ||::..::..:..|... |..|.:..|  :.:|.|: |.|.    .::: ||.: |
Zfish   349 SPQIWQHGTSLMNYLRMVEYDGLTGR-VEFNSKGQRTNYTLHILEKHRGG----HKEI-GIWYSN 407

  Fly   265 SAIVIAFPDLFTNI-EDLSLRH--IDTI-------SKVNHR--------------LMLELANRLN 305
            :.:::....|..|: |.|:.:.  |.||       .|:|::              ::.||::.|.
Zfish   408 NTLLMNSTSLDINVSETLANKSLIITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDILK 472

  Fly   306 MSYNTYQTVN---YGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDF--------VAE 359
            .:|. .:.|:   ||..:||||:.|::|.....:.|||..|..:..:|..::||        ::.
Zfish   473 FTYR-IKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISI 536

  Fly   360 TYRVRAGIMFRQPPLSAVANIFAMPFENDVWVSILMLLIITTVVLVLEL------FFSPHNHDMS 418
            .|||..|   |:|...:    |..||...||:.:|:..:..:.||.|..      :::||.....
Zfish   537 LYRVHIG---RKPGYFS----FLDPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYNPHPCLRE 594

  Fly   419 YMDTL-------NFVW---GAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALL--Q 471
            ..|.|       |.:|   |...|||..:..|..|.|.:....:...|.:.:|::||:.|.|  |
Zfish   595 RRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQ 659

  Fly   472 SPSDAIQSLSDLG-QSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENIYMRPL-LGME 534
            .....|:|..||. |:.::.|.........:|..|.....:.::: .:.||..:::::.. .|:.
Zfish   660 RMEVPIESPDDLADQTNIQYGTIHGGSTMTFFMNSRYQTYQRMWN-YMYSKQPSVFVKSTEEGIA 723

  Fly   535 KMRTGLFAYQVELQAGYQIVSDTFSEPEK---C------GLMELEPFQLPM-LAIPTRKNFPYKE 589
            ::....:|:.:|         .|.:|..:   |      ||::.:.:.:.| |..|.|.......
Zfish   724 RVVNSKYAFLLE---------STMNEYHRSLNCNLTQIGGLLDTKGYGIGMPLGSPFRDELSLAV 779

  Fly   590 LIRRQLRWQREVSLVNREERKWIPQK-PKCEG----GVGGFVSIGITECRYALGIFG---CGAAV 646
            |   ||:....:.::.|  |.|...| ||.|.    |: |..:||        |||.   ||..:
Zfish   780 L---QLQENNRLEILKR--RWWEGGKCPKEEDHRAKGL-GMENIG--------GIFVVLICGLII 830

  Fly   647 SFVLFLFEFIF 657
            :..:.:.||::
Zfish   831 AVFVAVMEFVW 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	25/83 (30%)
		Lig_chan	386..643	CDD:459656	65/294 (22%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	36..414	CDD:380616	41/200 (21%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:473866	87/392 (22%)