Protein Alignment Ir75d and Ekar

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 687
• Identity: 140/687 - (20%)
• Similarity: 260/687 - (37%)
• Gaps: 158/687 - (22%)

  Fly    54 YRHHGVHSLMLVVCHTDIADFRLWKLWQHFNLNNFYVQVSTESSLRD-LQHVDALDEHKDAPPPK 117
            |::|.:.:...:..: |:.||:    :...|:.:|.:..:.:..::. |:.:.....|....|..
  Fly   222 YKYHYLFTSFDLETY-DLEDFK----YNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYL 281

  Fly   118 SFHANNSTHWETSFLLPAL------PYKMGILLLEFSSECALNLLRWSAASEH---------NYF 167
            :.|...||..|:.   |||      .:.:|:..||.|.  :|.||..|...|:         ||.
  Fly   282 NLHIKKSTILESE---PALMFDSVYVFAIGLQTLEQSH--SLTLLNISCEEENSWDGGLSLINYL 341

  Fly   168 TTNRFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDL-----YKVAAWKP-- 225
            .... |..||   |.|...:...:                 .|...||.|     .||..|.|
  Fly   342 NAVE-WKGLT---GPIQFKDGQRV-----------------QFKLDLIKLKQHSIVKVGEWTPHG 385

  Fly   226 ---------------LKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLF 275
                           :..|||...|..:.:|   :.|:|...|..:...|...:.
  Fly   386 HLNITEPSMFFDAGSMNVTLVVITILETPYV---MMHYGKNFTGNERFYGFCVDI---------- 437

  Fly   276 TNIEDLSLRHIDTISK-VNHRLMLELA-NRLNMSYNTYQTVNYGWRQP-NGSFDGLMGRFQRYEL 337
                      ::|||: |....:|:|. :|           .||.:.| .|.::|::.:..:|:.
  Fly   438 ----------LETISREVGFDYILDLVPDR-----------KYGAKDPETGEWNGMVAQLMKYKA 481

  Fly   338 DLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLIIT 400
            |||..::.:...|.:::||......:...|:|: .|.|....:|:.  |...::|:.:|:...:.
  Fly   482 DLAVGSMTITYARESVIDFTKPFMNLGISILFK-VPTSEPTRLFSFMNPLAIEIWIYVLIAYFLV 545

  Fly   401 TVVLVLELFFSP---------------HNHDMSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFT 450
            ::.:.:....||               ..:..|..|:..|..|...||...:..|..|.|||..|
  Fly   546 SLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISST 610

  Fly   451 TFVAALFLFTSFSANIVALLQSPS--DAIQSLSDL-GQSPLEIGVQDTQYNKIYFTESTDPVTKN 512
            ....:|.:..|::||:.|.|.:..  :.|::..|| .|:.:..|..|:.....:|.:|.....|.
  Fly   611 WGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKK 675

  Fly   513 LYHKKIASKGENIYMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELEPFQLPML 577
            ::......|..........|::::..|.:|:.:|......||....:..:..||::.:.:
  Fly   676 IWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDYIVQRDCNLTQIGGLLDTKGY----- 735

  Fly   578 AIPTRKNFPYKELIR---RQLRWQREVSLV------NREE---RKWIPQKPKCEGGVGGFVSIGI 630
            .|.|.|..|:::.|.   .:|:.:.::.::      |.:|   ||...::.|...  .|..|||
  Fly   736 GIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANS--LGLESIG- 797

  Fly   631 TECRYALGIFG---CGAAVSFVLFLFEFIFRHFKQVY 664
                   |:|.   .|..|:.|:..|||.: :|:..|
  Fly   798 -------GVFVVLIAGIIVAAVVAFFEFWY-NFRYNY 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	16/74 (22%)
		Lig_chan	386..643	CDD:459656	57/289 (20%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	41/198 (21%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	80/408 (20%)
		Lig_chan	532..806	CDD:459656	57/288 (20%)