Protein Alignment Ir75d and GluRIA

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 138/760 - (18%)
• Similarity: 262/760 - (34%)
• Gaps: 234/760 - (30%)

  Fly    48 DMLVAYYRHHGVHSLMLVVCH--TDIADFRLWKLWQHFNLNNFYVQVSTESSLRDLQHVDALDEH 110
            |:.:....:|.:.|.:::..|  :|:.:|..      .|:..|.:..|...::||..     |..
  Fly   249 DIKLGRRTYHYLLSGLVMDNHWPSDVVEFGA------INITGFRIVDSNRRAVRDFH-----DSR 302

  Fly   111 KDAPPPKSFHANNSTHWETSFLLP------ALPYKMGILLLE----------------------- 146
            |...|.....:.|:....:   ||      ||.|....:|:|
  Fly   303 KRLEPSGQSQSQNAGGPNS---LPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSH 364

  Fly   147 --FSSECALNLLRWSAASEHNYFTTNRFWLLLTEDPGDID-LLEDPEIFIPPDSELRVLHYENVG 208
              .||..|......||..:.|   |::.|:...|....|. :|...||    |.....:.::..|
  Fly   365 GGSSSSSATGTNESSALLDCN---TSKGWVTPWEQGEKISRVLRKVEI----DGLSGEIRFDEDG 422

  Fly   209 ---NFSCSLID------LYKVAAWK------PLKRTLVGHNI---------------RNSRHVIH 243
               |::..:::      |.:||.|:      ||.    .||.               ||..:::.
  Fly   423 RRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLH----SHNYASSSRSASASTGDYDRNHTYIVS 483

  Fly   244 AL---------QHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHRLMLE 299
            :|         |:     ||.:.|.|   |.    .|.....::.|:
  Fly   484 SLLEEPYLSLKQY-----TYGESLVG---ND----RFEGYCKDLADM------------------ 518

  Fly   300 LANRLNMSY--NTYQTVNYGW--RQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAET 360
            ||.:|.:.|  ...|..|||.  :...|.:||::|...|.|.|:|..|:.:..:|..::||....
  Fly   519 LAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPF 583

  Fly   361 YRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLIITTVVLVLELFFSPHNHDM------ 417
            ..:...||.:: |:.....:|:.  |...::|:|:::..:..:.||.....|.|:...:
  Fly   584 MTLGISIMIKK-PVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQA 647

  Fly   418 ----------------------------SYMDTLNFVW---GAMCQQGFYVEVRNRSARIIVFTT 451
                                        :....||..|   .|..|||..:...:.:.||.....
  Fly   648 DSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVW 712

  Fly   452 FVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQ-DTQYNKI-------YFTESTDP 508
            :...:.|.:|::||:.|.|     .::.:....::|.::.:| |..|..:       :|..|...
  Fly   713 WFFTIILISSYTANLAAFL-----TVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIG 772

  Fly   509 VTKNLYHKKIASKGENIYMRPLLGMEKMR--TGLFAYQVE---------------LQAGYQI--- 553
            :...::....|::..:::... .|:.::|  .|.:|..||               ::.|..|
  Fly   773 LHNKMWEYMNANQHHSVHTYD-EGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTK 836

  Fly   554 ---VSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQK 615
               |:.....|.:..|.|         |:.|.|.  ..||:|.:.:|..:.:..|.::....|.:
  Fly   837 GFGVATPIGSPLRKRLNE---------AVLTLKE--NGELLRIRNKWWFDKTECNLDQETSTPNE 890

  Fly   616 PKCEGGVG-GFVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRH 659
            .......| .::.||             |..::.::.:.||..|:
  Fly   891 LSLSNVAGIYYILIG-------------GLLLAVIVAIMEFFCRN 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	46/226 (20%)
		Lig_chan	388..644	CDD:278489	52/324 (16%)
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	42/224 (19%)
		ANF_receptor	53..434	CDD:279440	38/205 (19%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	82/449 (18%)
		Lig_chan	612..907	CDD:278489	52/324 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840