Protein Alignment Ir75d and clumsy

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Alignment Length: 658
• Identity: 131/658 - (19%)
• Similarity: 230/658 - (34%)
• Gaps: 204/658 - (31%)

  Fly   116 PKSFHANNSTH-WE------------------TSFLL-----------------------PAL-- 136
            |..||..|..| ||                  :..:|                       |.|
  Fly   268 PSDFHVKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIFEELTAPDLEC 332

  Fly   137 ----PYKMGILLLEF----SSECALNLLRWSAASEHNYFT-------TNRFWLLLTEDP-GDIDL 185
                |:..|..::||    |.|.:...:.::...:.::||       ::.|..|.|.|| ..:|:
  Fly   333 RRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLATWDPVNGLDV 397

  Fly   186 LEDPEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGS 250
            |.|.|     :||.|                              ||..:.|...::.:  ..|:
  Fly   398 LNDDE-----ESEKR------------------------------VGQKLSNKTFIVSS--RLGA 425

  Fly   251 A-ITYRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMS----YNT 310
            . :|.|:..||.:....         :..|..|:..|:.|:|     ||.......||    |..
  Fly   426 PFLTLREPQEGEILTGN---------SRYEGYSIDLINEIAK-----MLNFKFEFRMSPDGKYGA 476

  Fly   311 YQTVNYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLS 375
            ...|...|       ||::.:......||....:.|...|...|||......:...|:|.:|| :
  Fly   477 LNKVTQTW-------DGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPP-T 533

  Fly   376 AVANIFAM--PFENDVWVSI------LMLLIITTVVLVLELFFSPH--------NHDMSYMDTLN 424
            ...::|:.  ||..|||:.:      :.||:.....:..:.:.:||        .:..|.|:|..
  Fly   534 PPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMNTTW 598

  Fly   425 FVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALLQS--PSDAIQSLSDL-GQS 486
            ...|::..||..:..:..|.|::....:..||.:..|::||:.|.|.:  .:::|.|..|| .||
  Fly   599 LSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQS 663

  Fly   487 PLEIGV----------QDTQ---YNKIY----------FTESTDPVTKNLYHKKIASKGENIYMR 528
            .::.|.          :|:.   |.|::          ||::.|...:.:      .||:|:|
  Fly   664 KIKYGAMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFTKTNDEGVERV------QKGKNLY-- 720

  Fly   529 PLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELE---PFQLPMLAIPTRKNFPYKEL 590
                ...|.:....|.||               .||.|:::.   .::...:|:|.  |.||::.
  Fly   721 ----AFLMESTTLEYNVE---------------RKCDLVQIGGWLDYKSYGIAMPF--NSPYRKQ 764

  Fly   591 IRRQLRWQREVSLVNREERKWIPQK------PKCEGGVGGFVSIGITECRYALGIFGCGAAVSFV 649
            |...:....|:..:...:|||..:.      .|.:...|....:|:........:.|.|...:.|
  Fly   765 ISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPELGLENVGGVFLVLGLGLLSAMV 829

  Fly   650 LFLFEFIF 657
            |...||::
  Fly   830 LGCTEFLW 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	16/76 (21%)
		Lig_chan	386..643	CDD:459656	60/305 (20%)
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	23/128 (18%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	90/425 (21%)