Protein Alignment Ir75d and Ir25a

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 837
• Identity: 150/837 - (17%)
• Similarity: 302/837 - (36%)
• Gaps: 248/837 - (29%)

  Fly    14 FLLVSGTPRVAGS---------WR------SEYSRQDPDPKTRWGNQLPDMLVAYYRHHGVHSLM 63
            |....|.|.::.|         ||      .:|..|...|    .:.:|:.:.:...|..:.:..
  Fly   122 FTQALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQVMPP----ADIIPEAIRSIVIHMNITNAA 182

  Fly    64 LVVCHTDIADFRLWKLWQ---------------------------HFNLNNFYVQVSTESSLRDL 101
            ::...:.:.|.:...|.|                           :.::|||:: :.|..|:|.:
  Fly   183 ILYDDSFVMDHKYKSLLQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFFI-LGTLQSIRMV 246

  Fly   102 QHVDALDEHKDAPPPKSF--HANNSTHWETS---------FLLPALPY-----KMGILLLEFSSE 150
                 |:..|.|...::|  ||......|.|         |:.| :.|     ::|:|...:
  Fly   247 -----LESVKPAYFERNFAWHAITQNEGEISSQRDNATIMFMKP-MAYTQYRDRLGLLRTTY--- 302

  Fly   151 CALNLLRWSAASEHNYF-TTNRFWLLLTED------PGDIDLL--EDPEIFIPPDSELRVLHY-- 204
               ||......|...|| ...|.:|.:.|.      |.|::.|  :|.:....|...|.:..|
  Fly   303 ---NLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFT 364

  Fly   205 -----ENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQ-HFGSAITYR---QDLEG 260
                 .:.|.|     ||. ..:.:|..    ||:.......|:.|| ..||::..:   :.:.|
  Fly   365 KITEPTSYGTF-----DLV-TQSTQPFN----GHSFMKFEMDINVLQIRGGSSVNSKSIGKWISG 419

  Fly   261 IVFNSAIVIAFPD------------LFTNIEDLSLRHIDTISKVNHRLMLELANRL----NMSYN 309
            :  ||.:::...:            :||.::...:...:|..|......::|.|.:    :..|
  Fly   420 L--NSELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETAPKGYKGYCIDLINEIAAIVHFDY- 481

  Fly   310 TYQTV---NYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETY-RVRAGIMFR 370
            |.|.|   .:|....||.::|::.:....:.|:...::.:..:|..::||....| .|...||.:
  Fly   482 TIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQ 546

  Fly   371 QPPLSAVANIFAMPFENDVWVSILMLLIITTVVLVLELFFSPHNH--------------DMSYMD 421
            :|...:....|....|.:||:.||.....|:.::.:...:||:::              :.:..:
  Fly   547 RPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKE 611

  Fly   422 TLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVAL-----LQSPSDAIQSLS 481
            .|.|...::..||.....:|.|.|::..|.::....:..|::||:.|.     |.:|   ::||.
  Fly   612 CLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTP---VESLD 673

  Fly   482 DLGQSPLEIGVQDTQYNKIYF-TESTDPVTKNLYHKKIASKGENIY--------MRPLLGMEKMR 537
            ||.:          ||..:|. ...:..:|   |.:::::..:..|        ...|..:|:.:
  Fly   674 DLAK----------QYKILYAPLNGSSAMT---YFERMSNIEQMFYEIWKDLSLNDSLTAVERSK 725

  Fly   538 TGLFAYQV--------------ELQA----------------GYQIVSDT----FSEPEKCGLME 568
            ..::.|.|              :|.|                |:..:.|.    :.:...|.|..
  Fly   726 LAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQV 790

  Fly   569 L-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQK--------PKCE----- 619
            : |.|.....||..::....|:.....:     ::|:|:.:.:.:.:|        .||:
  Fly   791 VGEEFSRKPYAIAVQQGSHLKDQFNNAI-----LTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQ 850

  Fly   620 ---------GGVGGFVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQVYRII 667
                     |||  |:.|.:            |..::.:..:||:.:..:::..|||
  Fly   851 SDGISIQNIGGV--FIVIFV------------GIGMACITLVFEYWWYRYRKNPRII 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	44/210 (21%)
		Lig_chan	388..644	CDD:278489	56/340 (16%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	63/332 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	74/419 (18%)
		Lig_chan	565..870	CDD:278489	56/339 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840