Protein Alignment Ir75d and GluRIIC

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 139/741 - (18%)
• Similarity: 248/741 - (33%)
• Gaps: 218/741 - (29%)

  Fly    81 QHFNLNNFYVQVSTESS-----LRDLQHVDALDEHKDAPPPKSFHANN-------STHWETSFLL 133
            |:|....|.:....:.:     |:||  :...:.|.|....:.||.::       |...|...:|
  Fly   153 QNFGWRKFTIVYDADDARAAARLQDL--LQLREVHNDVVRVRKFHKDDDFRVMWKSIRGERRVVL 215

  Fly   134 PALPYKMGILLLEFSSECAL----------NLLRWS-----AASEHNYFTTN--RFWLLLTEDPG 181
            ...| .|.:.||..|:|..|          ||..::     .|:::..|..|  ...||:..||.
  Fly   216 DCEP-NMLVELLNSSTEFGLTGQYNHIFLTNLETYTDHLEELAADNETFAVNITAARLLVNPDPP 279

  Fly   182 DIDL------LEDPEIFIPPDSELRVLH-------------YENVGNFSCSLIDLYKVA------ 221
            ...|      ..|..::...|....::|             :.|...|....:.:.::.
  Fly   280 PYSLPYGYVTQRDNIVYESSDPPRTLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAAS 344

  Fly   222 ---AW---KPLKRTLVG-HNIRNSRHVIHALQHFGSAITYRQDLEGIVFN-------SAIVIAFP 272
               .|   :.|.|.:.| ..:.|:......||       :.:|.:.|.||       ..|.||..
  Fly   345 GGRTWAMGRYLARLMKGTSGVNNTNFRTSILQ-------FDEDGQRITFNIEVYDPLDGIGIAIW 402

  Fly   273 DLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVNYGWRQPNGSFDGLMGRFQRYEL 337
            |....|..|   ::|.  |...:::..:|.|:...|.:|   |...|:.|.:.:.|   :|.|.:
  Fly   403 DPRGQITQL---NVDV--KAQKKMIYRVATRIGPPYFSY---NETARELNLTGNAL---YQGYAV 456

  Fly   338 DLAQLA--------IFM--------RLD------------------------------RIALVDF 356
            ||....        :|:        :||                              |...|||
  Fly   457 DLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDF 521

  Fly   357 VAETYRVRAGIM-FRQPPLSAVANIFAMPFENDVWVSILMLLIITTVVLVLELFFS------PH- 413
            .....::...|: ::.|.:....:.:..||..:||:.||:.:.:.|.:..:....|      ||
  Fly   522 TVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHP 586

  Fly   414 -NHDMSYMDTL----NFVW---GAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALL 470
             |.|...::..    |..|   .::...|..:..|:...|:...|.::.|:.:..|::||:.|.|
  Fly   587 CNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFL 651

  Fly   471 QSP--SDAIQSLSDL-GQSPLEIGV-------------QDTQYNKIY----------FT----ES 505
            .|.  ..:|.:|.|| .|..::.|.             .:|.|...:          :|    |.
  Fly   652 TSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEG 716

  Fly   506 TDPVTKNLYHKKIASKGENIYMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELE 570
            .|.|.||        :|:.:::        |.|....|..|.....:.|.:.|.|....
  Fly   717 VDRVRKN--------RGDYMFL--------METTTLEYHREQNCDLRSVGEKFGEKHYA------ 759

  Fly   571 PFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKC--EGGVGGFVSIGITEC 633
                  :|:|....: ...|....|:......|.:.:::.|......|  |........:...|.
  Fly   760 ------IAVPFGAEY-RSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTFEEL 817

  Fly   634 RYALGIF---GCGAAVSFVLFLFEFI 656
            |   |||   ..|..::|::.:.||:
  Fly   818 R---GIFYTLYAGILIAFLIGITEFL 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	48/247 (19%)
		Lig_chan	388..644	CDD:278489	58/305 (19%)
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	49/260 (19%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	10/83 (12%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	73/405 (18%)
		Lig_chan	554..828	CDD:278489	58/305 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940