Protein Alignment Ir75d and Nmdar2

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 126/646 - (19%)
• Similarity: 207/646 - (32%)
• Gaps: 223/646 - (34%)

  Fly    76 LWKLWQHFNLNNFYVQVSTESSLRDLQHVDALDEHKDAPP---PKSFHANNSTHWETSF--LLPA 135
            :||.|:...|:           :||:    |...:..|||   |:.||...:...|..:  |.||
  Fly   472 VWKSWETQKLD-----------IRDI----AWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPA 521

  Fly   136 LPYKMGILLLEFSSECALN---LLRWSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDS 197
            .|         .|.:|.::   |.|  .|::|             |...|||
  Fly   522 DP---------VSGKCLMDRGVLCR--VAADH-------------EMAADID------------- 549

  Fly   198 ELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIV 262
                                             ||...||.              ::.|...|..
  Fly   550 ---------------------------------VGQAHRNE--------------SFYQCCSGFC 567

  Fly   263 FNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVNYGW-RQPNGSFD 326
                                   ||.:.|        .|..|..:|...:..:..| ...||.::
  Fly   568 -----------------------IDLLEK--------FAEELGFTYELVRVEDGKWGTLENGKWN 601

  Fly   327 GLMGRFQRYELDLAQLAIFMRLDRIALVDF--------VAETYRVRAGIMFRQPPLSAVANIFAM 383
            ||:......:.|:...::.:..:|.|:|||        :|.....|.||      :|..|  |..
  Fly   602 GLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGI------ISPTA--FLE 658

  Fly   384 PFENDVW--VSILMLLIITTVVLVLELFFSPHNHDMS-YMDTLN-------------FVWGAMCQ 432
            ||:...|  |.|:.:...|.::.:.| :.||..:||. |:...|             .||..:.|
  Fly   659 PFDTASWMLVGIVAIQAATFMIFLFE-WLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQ 722

  Fly   433 QGFYVE-VRNRSARIIVFTTFVAALF---LFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQ 493
            ...:|: .|..::|   |.|.|.|||   ....::||:.|.:.: .:.....|.|..|.|   |.
  Fly   723 AAVHVDSPRGFTSR---FMTNVWALFAVVFLAIYTANLAAFMIT-REEFHEFSGLNDSRL---VH 780

  Fly   494 DTQYNKIY--------FTESTDPVTKNLYHKKIASKGENIYMRPLL------GMEKMRTG---LF 541
            ...:...:        .|:||.....|:.|.         |||...      |:..:..|   .|
  Fly   781 PFSHKPSFKFGTIPYSHTDSTIHKYFNVMHN---------YMRQYNKTSVADGVAAVLNGNLDSF 836

  Fly   542 AYQVELQAGYQIVSDTFSEPEKCGLMELEP-FQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVN 605
            .|...: ..|.:..|     |.|.||.:.. :.:....:...:|..|.::..::|...|....:.
  Fly   837 IYDGTV-LDYLVAQD-----EDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLE 895

  Fly   606 REERKWIPQKPKCEGGVGGFVS---IGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQV 663
            |..|.|:  ...|..|.....|   :.:.:...|..:...|..::.:|.|.|.::  ||.:
  Fly   896 RLRRYWM--TGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVY--FKYI 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	50/212 (24%)
		Lig_chan	388..644	CDD:278489	60/296 (20%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	7/32 (22%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	106/553 (19%)
		Lig_chan	665..928	CDD:278489	59/287 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840