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Protein Alignment Ir75d and Gria3

DIOPT Version :9

Sequence 1:	NP_649074.2	Gene:	Ir75d / 40065	FlyBaseID:	FBgn0036829	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_001106213.1	Gene:	Gria3 / 29628	RGDID:	70958	Length:	888	Species:	Rattus norvegicus

Alignment Length:	713	Identity:	145/713 - (20%)
Similarity:	259/713 - (36%)	Gaps:	188/713 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NQLPDMLVAYYRH-HGVHSLMLVVCHTDIADFRLWKLWQH--FNLNNFYVQVSTESSL--RDLQH 103
            |.:.:.:|...:| .|.|.::..:..|||    |.:...|  .|:..|.: |:.|:.:  :.:|.
  Rat   221 NTILEQVVILGKHSRGYHYMLANLGFTDI----LLERVMHGGANITGFQI-VNNENPMVQQFIQR 280

  Fly   104 VDALDEH-----KDAPPPKSFHANNSTHWETSFLL---------------------------PAL 136
            ...|||.     |:||..   :.:..||  .:.|:                           ||:
  Rat   281 WVRLDEREFPEAKNAPLK---YTSALTH--DAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAV 340

  Fly   137 PYKMGILLLEFSSECALNLLRWSAASEHNYFTTNRFWLLLTEDPGDIDLLE-------------D 188
            |:..||     ..|.||.:::....:.:..|.|.......|     ||:.|             :
  Rat   341 PWSQGI-----DIERALKMVQVQGMTGNIQFDTYGRRTNYT-----IDVYEMKVSGSRKAGYWNE 395

  Fly   189 PEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAIT 253
            .|.|:|       ...:.:.|.|.|           ...||:|...|..|.:|::...|
  Rat   396 YERFVP-------FSDQQISNDSSS-----------SENRTIVVTTILESPYVMYKKNH------ 436

  Fly   254 YRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHR-------LMLELANRLNMSY--N 309
              :.|||                                |.|       |..|:|..:.:.|  :
  Rat   437 --EQLEG--------------------------------NERYEGYCVDLAYEIAKHVRIKYKLS 467

  Fly   310 TYQTVNYGWRQPNGS-FDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPP 373
            ......||.|.|... ::|::|.......|:|...:.:.|.|..::||......:...||.::|.
  Rat   468 IVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 532

  Fly   374 LSAVANIFAM--PFENDVWVSILMLLIITTVVLVLELFFSPHN--------------------HD 416
            .|. ..:|:.  |...::|:.|:...|..:|||.|...|||:.                    ::
  Rat   533 KSK-PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNE 596

  Fly   417 MSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALLQ-----SPSDA 476
            ....::|.|..||..|||..:..|:.|.||:....:...|.:.:|::||:.|.|.     ||
  Rat   597 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP--- 658

  Fly   477 IQSLSDLG-QSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENIYMRPLL-GMEKMR-- 537
            |:|..||. |:.:..|..|:...|.:|..|...|.:.:: ..:.|...:::.:... |:.::|
  Rat   659 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW-SYMKSAEPSVFTKTTADGVARVRKS 722

  Fly   538 TGLFAYQVELQAGYQIVSDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREV 601
            .|.||:.:|     ..:::...:.:.|..|:: .........:.|.|.......:...:....|.
  Rat   723 KGKFAFLLE-----STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQ 782

  Fly   602 SLVNREERKWIPQKPKCEGGVGGFVSIGITECRYALGIFGC------GAAVSFVLFLFEFIFR 658
            .|:::.:.||...|.:|  |.||..|...|.......:.|.      |..::.::.|.||.::
  Rat   783 GLLDKLKNKWWYDKGEC--GSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYK 843

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.