Protein Alignment Ir75d and GRIN2C

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 104/479 - (21%)
• Similarity: 175/479 - (36%)
• Gaps: 119/479 - (24%)

  Fly    90 VQVSTES-------SLRDLQHVDALDEHKDAPPPKSFHANNSTHWETSFLLPALPYKMGILLLEF 147
            :.|.|||       .:||...:.||..|              ::|.....||| |
Human   349 ISVVTESWRLSLRQKVRDGVAILALGAH--------------SYWRQHGTLPA-P---------- 388

  Fly   148 SSECALNLLRWSAASEHNYFTTNRFWLLLTEDPGDIDL-----LEDPEIFIPPDSELRVLHYENV 207
            :.:|.::....|.|.|..|    |..|.:|.:..|...     |..|.:.:...:..|:  :|.|
Human   389 AGDCRVHPGPVSPAREAFY----RHLLNVTWEGRDFSFSPGGYLVQPTMVVIALNRHRL--WEMV 447

  Fly   208 GNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHV-IHALQHFGSAITYRQD--LEGIV------- 262
            |.:...::.: |...|.....:|  ..:.:|||: :..|:.....|....|  ..|.|
Human   448 GRWEHGVLYM-KYPVWPRYSASL--QPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCR 509

  Fly   263 ------FNSAIVIAFPDL----FTNIEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVN-- 315
                  |:|..|..:..|    |.         ||.:.|        ||..:..||:.|...|
Human   510 RQSNHTFSSGDVAPYTKLCCKGFC---------IDILKK--------LARVVKFSYDLYLVTNGK 557

  Fly   316 YGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANI 380
            :| ::..|.::|::|.......|:|..::.:..:|..:|||..........:|..:...:...:.
Human   558 HG-KRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSA 621

  Fly   381 FAMPFENDVWVS--ILMLLIITTVVLVLELFFSPHNHDMSYMDTLN-----------------FV 426
            |..|:...|||.  ::.|.::...|.:.| :|||    :||...|.                 .:
Human   622 FLEPYSPAVWVMMFVMCLTVVAITVFMFE-YFSP----VSYNQNLTRGKKSGGPAFTIGKSVWLL 681

  Fly   427 WGAMCQQGFYVE-VRNRSARIIVFT-TFVAALFLFTSFSANIVALL--QSPSDAIQSLSDLGQSP 487
            |..:......:| .|..:::|:|.. .|.|.:|| .|::||:.|.:  :...|.:..|||.....
Human   682 WALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFL-ASYTANLAAFMIQEQYIDTVSGLSDKKSLH 745

  Fly   488 LE-IGVQDTQYNKI---YFTESTD 507
            || .||..|.:...   ||....|
Human   746 LENTGVAWTAFKTFCSDYFQRPQD 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	47/208 (23%)
		Lig_chan	388..644	CDD:278489	37/147 (25%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156118
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740