Protein Alignment Ir75d and GRID2

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 93/482 - (19%)
• Similarity: 196/482 - (40%)
• Gaps: 96/482 - (19%)

  Fly   219 KVAAWKP---LKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTN--- 277
            ::..|.|   |..:|....:.|                   ::.|:|.....|:..|.:..:
Human   443 QLGCWNPVTGLNGSLTDKKLEN-------------------NMRGVVLRVVTVLEEPFVMVSENV 488

  Fly   278 ------IEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVN--YGWRQPNGSFDGLMGR--F 332
                  .:..|:..:|.:|           |.|..:|..|...:  ||..|.:|:::||:|.  |
Human   489 LGKPKKYQGFSIDVLDALS-----------NYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVF 542

  Fly   333 QRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFA--MPFENDVWVSILM 395
            :|.::.::.|.|  ..||..:|||.........|::.|:  .....::||  .||:..:|..|..
Human   543 KRADIGISALTI--TPDRENVVDFTTRYMDYSVGVLLRR--AEKTVDMFACLAPFDLSLWACIAG 603

  Fly   396 LLIITTVVLVLELFFSPHNHDMSYM------DTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVA 454
            .:::..:::.|..:.:|....|..|      :::.||:|:..|||..|.....:.|:::...::.
Human   604 TVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLF 668

  Fly   455 ALFLFTSFSANIVALLQSP--SDAIQSLSDLG-QSPLEIG-VQDTQYNKIYFTESTDPVTKNLYH 515
            ||.:.:|::||:.|.|...  ..:||||.||. |:.:..| |.|:...:....:..:|..::..:
Human   669 ALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMY 733

  Fly   516 KKI------ASKGENIYMRPLLGMEKMRTGLFAYQVEL-----------QAGYQIVSDTFSEPEK 563
            .::      ::..||..:....|::|::.|.:|:..:.           ...:..:.:|.::..
Human   734 SQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRG- 797

  Fly   564 CGLMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCE--GGVGGFV 626
                         ..|..:...||:::..:::...::...::..:.||.|:..:|:  ..|....
Human   798 -------------YGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQ 849

  Fly   627 SIGITECRYALGIFGCGAAVSFVLFLF 653
            ..|..:.:...|:| |..|...||..|
Human   850 KGGALDIKSFAGVF-CILAAGIVLSCF 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	51/197 (26%)
		Lig_chan	388..644	CDD:278489	51/284 (18%)
GRID2	XP_011530195.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740