Protein Alignment Ir75d and GRIA1

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001244950.1
• Gene: GRIA1 / 2890
• HGNCID: 4571
• Length: 916
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 96/415 - (23%)
• Similarity: 178/415 - (42%)
• Gaps: 54/415 - (13%)

  Fly   296 LMLELANRLNMSYNTYQTVN---YGWRQPN-GSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDF 356
            |..|:|..:..||. .:.|:   ||.|.|: .:::|::|.......|:|...:.:.|.|..::||
Human   452 LAAEIAKHVGYSYR-LEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDF 515

  Fly   357 VAETYRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLIITTVVLVLELFFSPH------ 413
            ......:...||.::|..|. ..:|:.  |...::|:.|:...|..:|||.|...|||:
Human   516 SKPFMSLGISIMIKKPQKSK-PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEE 579

  Fly   414 ------------NHDMSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANI 466
                        :::....::|.|..||..|||..:..|:.|.||:....:...|.:.:|::||:
Human   580 FEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANL 644

  Fly   467 VALLQ-----SPSDAIQSLSDLG-QSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENI 525
            .|.|.     ||   |:|..||. |:.:..|..:....|.:|..|...|.:.:: ..:.|...::
Human   645 AAFLTVERMVSP---IESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMW-TYMKSAEPSV 705

  Fly   526 YMRPL-LGMEKMR--TGLFAYQVELQAGYQIVSDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFP 586
            ::|.. .||.::|  .|.:||.:|     ..:::...:.:.|..|:: .........|.|.|...
Human   706 FVRTTEEGMIRVRKSKGKYAYLLE-----STMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 765

  Fly   587 YKELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVGGFVSIGITECRYALGIFGC------GAA 645
            .:..:...:....|..|:::.:.||...|.:|  |.||..|...|.......:.|.      |..
Human   766 LRNPVNLAVLKLNEQGLLDKLKNKWWYDKGEC--GSGGGDSKDKTSALSLSNVAGVFYILIGGLG 828

  Fly   646 VSFVLFLFEFIFRHFKQVYRIIKGY 670
            ::.::.|.||.::...:..| :||:
Human   829 LAMLVALIEFCYKSRSESKR-MKGF 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	54/212 (25%)
		Lig_chan	388..644	CDD:278489	65/289 (22%)
GRIA1	NP_001244950.1	PBP1_iGluR_AMPA_GluR1	36..399	CDD:107385
		ANF_receptor	47..382	CDD:279440
		PBP2_iGluR_AMPA_GluR1	416..797	CDD:270447	82/355 (23%)
		Lig_chan	548..827	CDD:278489	65/289 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156049
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840