Protein Alignment Ir75d and Grin3a

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001263284.1
• Gene: Grin3a / 242443
• MGIID: 1933206
• Length: 1135
• Species: Mus musculus
• Alignment Length: 574
• Identity: 110/574 - (19%)
• Similarity: 203/574 - (35%)
• Gaps: 139/574 - (24%)

  Fly   161 ASEHNYFTTN--------RFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDL 217
            :||:|:|..|        ..|..|....|. .::.|..|: |..::....|:.:.......::
Mouse   458 SSENNFFIWNLQYDPMGKPMWTRLGSWQGG-RIVMDSGIW-PEQAQRHKTHFHHPNKLHLRVV-- 518

  Fly   218 YKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIEDLS 282
                       ||:.|....:|.|               |.||:.....:.:   |..||  |.|
Mouse   519 -----------TLIEHPFVFTREV---------------DDEGLCPAGQLCL---DPMTN--DSS 552

  Fly   283 LRHIDTISKVNHR-------------------LMLELANRLNMSYNTYQTVN--YG-WRQPNGSF 325
            :  :|::....|.                   |:.:||..:|..::.|...:  || |:  ||.:
Mouse   553 I--LDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NGHW 613

  Fly   326 DGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAMPFENDVW 390
            .||:|.......::|..:..:...|..::||.:..:....||:.|....:|....|..|....:|
Mouse   614 TGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMW 678

  Fly   391 VSILMLLIITTVVLVLELFFSP---------HNHDMSYMDTLNFVWGAMCQQGFYVEVRNRSA-- 444
            :.|.:.|.||.:.|.|..:.||         .|...|:...||     :|    |..:..|:|
Mouse   679 LGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALN-----VC----YALLFGRTAAI 734

  Fly   445 --------RIIVFTTFVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQDTQYNKIY 501
                    |.::....:..:|..::::||:.|::.. ....:.||.:....|....|..::..:.
Mouse   735 KPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVG-EKIYEELSGIHDPKLHHPSQGFRFGTVR 798

  Fly   502 FTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKMRT------------GLFAYQVELQAGYQIV 554
            .:.:.|.|.::........:..|:...| .|::.::.            .|..|:|.:.|
Mouse   799 ESSAEDYVRQSFPEMHEYMRRYNVPATP-DGVQYLKNDPEKLDAFIMDKALLDYEVSIDA----- 857

  Fly   555 SDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKC 618
                    .|.|:.: :||.:....|....|.|....|...:...:....::....||....| |
Mouse   858 --------DCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVP-C 913

  Fly   619 EGGVGGFVSIGITE-----CRYALGIFGCGAAVSFVLFLFEFIFRHFKQVYRII 667
                 |..|..:||     .::..|:|.. ..:.|.|.:...|..|.  |||::
Mouse   914 -----GKRSFAVTETLQMGIKHFSGLFVL-LCIGFGLSILTTIGEHI--VYRLL 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	46/205 (22%)
		Lig_chan	388..644	CDD:278489	53/292 (18%)
Grin3a	NP_001263284.1	PBP1_iGluR_NMDA_NR3	30..497	CDD:107372	10/40 (25%)
		PBP2_iGluR_NMDA_Nr3	512..908	CDD:270438	82/456 (18%)
		Lig_chan	676..942	CDD:278489	53/296 (18%)
		PPP2CB binding site. /evidence=ECO:0000250|UniProtKB:Q9R1M7	951..987		4/11 (36%)
		GIT1-binding. /evidence=ECO:0000250|UniProtKB:Q9R1M7	1082..1115

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830