Protein Alignment Ir75d and Grin3a

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_612555.1
• Gene: Grin3a / 191573
• RGDID: 621704
• Length: 1135
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 109/576 - (18%)
• Similarity: 202/576 - (35%)
• Gaps: 143/576 - (24%)

  Fly   161 ASEHNYFTTNRFWLLLTEDP--------------GDIDLLEDPEIFIPPDSELRVLHYENVGNFS 211
            :||:|:|..|     |..||              |.|  :.|..|: |..::....|:::.....
  Rat   458 SSENNFFIWN-----LQHDPMGKPMWTRLGSWQGGRI--VMDSGIW-PEQAQRHKTHFQHPNKLH 514

  Fly   212 CSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFT 276
            ..::             ||:.|....:|.|               |.||:.....:.:   |..|
  Rat   515 LRVV-------------TLIEHPFVFTREV---------------DDEGLCPAGQLCL---DPMT 548

  Fly   277 NIEDLSLRHIDTISKVNHR---------------LMLELANRLNMSYNTYQTVN--YG-WRQPNG 323
            |...:..|...::...|..               |:.:||..:|..::.|...:  || |:  ||
  Rat   549 NDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWK--NG 611

  Fly   324 SFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAMPFEND 388
            .:.||:|.......::|..:..:...|..::||.:..:....||:.|....:|....|..|....
  Rat   612 HWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWT 676

  Fly   389 VWVSILMLLIITTVVLVLELFFSP---------HNHDMSYMDTLNFVWGAMCQQGFYVEVRNRSA 444
            :|:.|.:.|.||.:.|.|..:.||         .|...|:...||     :|    |..:..|:|
  Rat   677 MWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALN-----VC----YALLFGRTA 732

  Fly   445 ----------RIIVFTTFVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQDTQYNK 499
                      |.::....:..:|..::::||:.|::.. ....:.||.:....|....|..::..
  Rat   733 AIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVG-EKIYEELSGIHDPKLHHPSQGFRFGT 796

  Fly   500 IYFTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKMRT------------GLFAYQVELQAGYQ 552
            :..:.:.|.|.::........:..|:...| .|::.::.            .|..|:|.:.|
  Rat   797 VRESSAEDYVRQSFPEMHEYMRRYNVPATP-DGVQYLKNDPEKLDAFIMDKALLDYEVSIDA--- 857

  Fly   553 IVSDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKP 616
                      .|.|:.: :||.:....|....|.|....|...:...:....::....||....|
  Rat   858 ----------DCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVP 912

  Fly   617 KCEGGVGGFVSIGITE-----CRYALGIFGCGAAVSFVLFLFEFIFRHFKQVYRII 667
             |     |..|..:||     .::..|:|.. ..:.|.|.:...|..|.  |:|::
  Rat   913 -C-----GKRSFAVTETLQMGIKHFSGLFVL-LCIGFGLSILTTIGEHI--VHRLL 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	46/205 (22%)
		Lig_chan	388..644	CDD:278489	53/292 (18%)
Grin3a	NP_612555.1	PBP1_iGluR_NMDA_NR3	30..497	CDD:107372	12/46 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..117
		ANF_receptor	127..469	CDD:279440	5/15 (33%)
		PBP2_iGluR_NMDA_Nr3	512..908	CDD:270438	80/452 (18%)
		Lig_chan	676..942	CDD:278489	53/296 (18%)
		PPP2CB binding site	951..987		3/11 (27%)
		GIT1-binding. /evidence=ECO:0000269|PubMed:24297929	1082..1115

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350003
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830