Protein Alignment Ir75d and glr-6

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_741822.2
• Gene: glr-6 / 180955
• WormBaseID: WBGene00001617
• Length: 844
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 104/518 - (20%)
• Similarity: 199/518 - (38%)
• Gaps: 116/518 - (22%)

  Fly   196 DSELRVLHYENVGNFSCSL-IDLYKVAAWKPLKR-TLVGHNIRNSRHVIHALQHFGSAITYRQDL 258
            |||   ||...:|.....| ..::| :.|:..|. |::..||..:.      :|:.:::...:.|
 Worm   357 DSE---LHIWEMGITGAGLHTGIWK-STWEGSKELTMLAKNIPGTH------EHYQASVRESRTL 411

  Fly   259 EGIVFNSAIVIAFPDLFTNIED--LSLRHIDTISKVNHR-----LMLELANRLNMSYNTYQTV-- 314
            :               .|:|.:  ..:..|....::.|.     |:.:||..|:.:| |.:.|
 Worm   412 K---------------VTSIHEKPYVIEKIMPDGRIKHEGFCVDLLDKLAEMLHFNY-TLKIVKD 460

  Fly   315 -NYGWRQPNGS--FDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSA 376
             .||.|: ||:  :||::|...|.:.|:|...|.:...|:.::||.....::...::.|||...:
 Worm   461 NKYGERK-NGTDEWDGMIGEILRGDADMAVAPITVTATRLEVIDFTDPFLQLGISMLMRQPNPKS 524

  Fly   377 VANI--FAMPFENDVWVSILMLLIITTVVLVLELFFSPHNHDMSYMDTLNFVW-----------G 428
            .:::  |..|....||....:..:||.:::.:....||......: ...|.||           |
 Worm   525 SSSLTRFLWPLSASVWTFSAIATVITALLVTVAAVLSPKESTAEF-KIQNSVWYLVCILLRAGSG 588

  Fly   429 AMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALL--QSPSDAIQSLSDLGQSPLEIG 491
            ..||.|        :.|:|....:...|.|...::||..|||  ...|....|..:||
 Worm   589 YNCQAG--------ATRLISAVWWSFTLVLIAQYTANFAALLTVDRKSMPFNSFEELG------- 638

  Fly   492 VQDTQYN---------KIYFTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKMRTGLFAYQVE- 546
             ..|:||         ..:|..|.....:.|:.:..:::..........|:.::....:.:.:|
 Worm   639 -NQTEYNFGSILGGSTMQFFKYSRIETFRRLWERMQSAEPSAFVGTNHEGVNRVLNEKYVFLMES 702

  Fly   547 LQAGYQIVSDTFSEPEKCGLMELEPFQLP----MLAIPTRKNFPYKELIRRQLRWQREVSLVNRE 607
            ....||:.       :.|.|..:....|.    .:|:|  |...::|.:.||:....|..::...
 Worm   703 ATLDYQVT-------QNCNLTRVGNVVLGSNGYSIALP--KGSKWREKLTRQILDLNEKGIILML 758

  Fly   608 ERKWIPQ-KPKCEGGVGGFVSIGITECRYALG---IFG------CGAAVSFVLFLFE---FIF 657
            :..|..: :.:|:       |....:.:.|||   ::|      .|:.:..:..:.|   |||
 Worm   759 KNNWWKKSQQECQ-------SSEPEDLQTALGAENVYGLFLLLALGSGIGVLCAVLEHTHFIF 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	22/77 (29%)
		Lig_chan	386..643	CDD:459656	53/293 (18%)
glr-6	NP_741822.2	PBP1_iGluR_non_NMDA-like	21..394	CDD:380591	11/40 (28%)
		PBP2_iGluR_Kainate	409..764	CDD:270432	79/397 (20%)