Protein Alignment Ir75d and glr-5

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_505244.1
• Gene: glr-5 / 179251
• WormBaseID: WBGene00001616
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 795
• Identity: 159/795 - (20%)
• Similarity: 285/795 - (35%)
• Gaps: 242/795 - (30%)

  Fly    45 QLPDMLVAYYRHHGVHSLMLVVCHTDIADFRLWKLWQ------HFNLNNFYVQVSTESSLRDLQH 103
            ||.:.:|..:.|...:.::||.    ..|.|:.:|.|      :.::..:.::|.....::..:.
 Worm   136 QLFEAVVDMFTHWRWNRIVLVY----EGDERIRRLEQLLESEEYASIRFYLIKVHDGDYMKAARQ 196

  Fly   104 VDALDE----HK-----------DAPPPKSFHANNSTHWETSFLLPALPYKMGILLLEF------ 147
            |..|:|    ||           |..|..::          :|||.:|  :||::.|:.
 Worm   197 VKELEECRLLHKKDCSEFSRLLVDMNPEHTY----------TFLLASL--QMGLIELKHWFLLTN 249

  Fly   148 --SSECALNLLRWSAAS-------EHNYFTTNR--------------FWLLLTEDPGDIDLLEDP 189
              .|...:.|.|::.|.       :..:.|.||              .|.:.|::..::.::|..
 Worm   250 MELSTMDMELFRYNHARFISPYPVDSTFLTENRDAFNFSHFKEHITEKWAMKTDNSRNLKMMEAV 314

  Fly   190 EIFIPPDSELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITY 254
            ..|   |:   |..:.||.|...|.:.:..|      .:||...:.||||...|......:.:
 Worm   315 FTF---DA---VYAFANVFNELSSHMQMNDV------PQTLCRKSSRNSRKYQHGRSLIDNIV-- 365

  Fly   255 RQDLEGIV--------------FNSAIV----------IAFPDLFTNI----------------- 278
            ..||.|:.              |:..|.          |.|.:..||:
 Worm   366 HNDLHGLSGDLRRLNGHPLKSNFSMRIQLLGYSGRLDDIGFWEPATNVHVNMSGDSKAQLQRNVQ 430

  Fly   279 --EDLSLR-HIDTIS-------KVNH--------------RLMLELANRLNMSY-------NTYQ 312
              ::|... .:.||.       |.||              .|:.||:..|..:|       ..|.
 Worm   431 VSDELKPHFRVTTIMERPYVMLKKNHYELDANSKFEGFCIDLLAELSKDLGFTYTIHAVKDGKYG 495

  Fly   313 TVNYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFR-----QP 372
            ...||    |||:||:||...|.|.::|...:.:...|...|||......:...|:::     ||
 Worm   496 NDKYG----NGSWDGMMGEILRGEAEMAVAPLTVNYRRSEAVDFTKPFLSLGISILYKVPDDQQP 556

  Fly   373 PLSAVANIFAMPFENDVWVSILMLLIITTVVLVL---------ELFFS------PH--------- 413
            .|.:..|    |....:|.:|...:|..|:.:..         .|.||      ||
 Worm   557 DLFSFLN----PLSWQIWTAIATSIITVTLGMYFVANVTPYEWNLNFSCCTAHEPHPAAAFATNQ 617

  Fly   414 ------NHDMSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALL-- 470
                  :::.|:.:|:.:|...|.:.|.....|..|.|::..|.:|..|.:.::::||:.|:|
 Worm   618 EAPIVMSNNYSFWNTVWYVLSTMLKGGCDFGPRAVSTRLLGGTWWVFYLVIISAYTANLAAVLTV 682

  Fly   471 QSPSDAIQSLSDL-GQSPLEIGVQDTQYNKIYFTESTDPVTKNL--YHKK----IASKGENIYMR 528
            ..|...|::|.|| .|:.:..|.........:|.||.......:  |.|.    :.|.|:
 Worm   683 SRPYIPIKNLDDLANQTTISYGTIRGGSTMQFFQESRIAAHVKMWQYMKDKDVFVTSNGK----- 742

  Fly   529 PLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMEL------EPFQLPMLAIPTRKNFPY 587
               |:|:..:..:||.:|      ..|..:...:.|.|.::      :.:     .|...|...:
 Worm   743 ---GVERALSMNYAYLME------STSLEYETQQNCNLTQIGGVLGSKGY-----GIALAKKSEW 793

  Fly   588 KELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVGGFVSIGITECRYAL------GIF---GCG 643
            .:.|.||:....:..::..::.||...|    |......:..:...|:||      |:|   |.|
 Worm   794 TDRISRQILLYAKRGIIEMKKTKWWRSK----GAACASTASAVKHDRFALSMYNVAGLFITLGVG 854

  Fly   644 AAVSFVLFLFEFIFR 658
            ..::.::.:||.|.|
 Worm   855 IVLAAIVVIFELIHR 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	54/227 (24%)
		Lig_chan	388..644	CDD:278489	61/309 (20%)
glr-5	NP_505244.1	PBP1_iGluR_delta_like	26..418	CDD:107376	59/311 (19%)
		ANF_receptor	38..377	CDD:279440	53/270 (20%)
		PBP2_iGluR_Kainate	438..819	CDD:270432	86/407 (21%)
		Lig_chan	568..855	CDD:278489	61/309 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910