Protein Alignment Ir75d and glr-4

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001254126.1
• Gene: glr-4 / 174258
• WormBaseID: WBGene00001615
• Length: 951
• Species: Caenorhabditis elegans
• Alignment Length: 857
• Identity: 164/857 - (19%)
• Similarity: 310/857 - (36%)
• Gaps: 237/857 - (27%)

  Fly     9 LPLIFFLLVS--------GTPRVAGSWRSEYSRQDPDPKTRWGNQLPDMLVAYYRHHGVH----- 60
            |.:||::..|        ||....||:..|:.|...|   ||..:           ||.|
 Worm    14 LLVIFYIANSAADDRFHIGTIANRGSFAYEHLRYAID---RWNTE-----------HGAHTQIKF 64

  Fly    61 SLMLVVCHTDIADFRLWKLWQHFNLNNFYVQVSTESSLRDLQHVDALDEHKDAP----------- 114
            |::..:.:.:..:.|:.::.|.   ....|.:|.|.|.:|.|.:.::..:.:.|
 Worm    65 SIVSPIRYDNNYEERMCEIMQQ---GIVAVVLSNEESEQDSQLIKSMCHYFNIPCLSLQSTSLRD 126

  Fly   115 ----------PPKSFHAN------NSTHWETSFLL------------PALPYK-----------M 140
                      |.:...|.      :|..| |.|||            |.:.||           :
 Worm   127 SVSDFVTLLGPSRGAGARATSEFLDSMRW-TGFLLAYQHGSDLEDLSPLMQYKQIVDTGGRRIHI 190

  Fly   141 GILLLEFSS---ECALNLLRWSAASEHNYFTTNRFWLL--LTEDPGDIDLLEDPEIFIPPDSELR 200
            .|..|..::   |..|..::......:....:|...:|  |.:....:::.|.|..::..:::|.
 Worm   191 KIRRLPNNTDDYEPFLKYVKTRLKQTNIIIHSNNITVLYNLLQQARGLNMAEPPFSYVFTNTDLS 255

  Fly   201 VLH--YENV--GNFSCSLIDLYKVAAWKPLKRT----------LVGHNIRNSRHVIHALQHFGSA 251
            :|.  ..|:  .:|.|::..|..|.. .|:.:|          :||.:|...|.:.||.:. .|.
 Worm   256 LLEDFLNNMYGASFHCNITGLQLVKN-DPMMKTQLALTSEAVYVVGMSIYRMRELGHAPRQ-SSI 318

  Fly   252 ITYRQDL--EGIVFNSAI-----------VIAFP------------------------------- 272
            :....|:  :|.:.|..|           .:.|.
 Worm   319 MCDSHDIWSDGRIMNEGIRKLKLRNQLTGDVQFKSNGERDDIMYHGVGRINSQFVKLGNWSEKRG 383

  Fly   273 -------------DLFTNIEDLSLRHIDTISKVNH----------------RLMLELANRLNMSY 308
                         |:..:.|||...|:..:..:..                .|:.|:...|..:|
 Worm   384 WNFDSRYANRWEFDIDPDSEDLEGLHLRVVVYLEEPFVIKTGENQYEGFCIDLLNEMTQVLKFNY 448

  Fly   309 N--TYQTVNYGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQ 371
            .  ..|...||....:|.::|::|..||:|.||:..|:.:...|..:|||......:...|:..:
 Worm   449 TIIEVQDGTYGIEDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFMHLGISILLAR 513

  Fly   372 PPLSAVAN---IFAMPFENDVWVSILMLLIITTVVLVLELFFSPHN-HDMSYMD----------- 421
            ........   .|..|....||:|:|:...|.:..:.:...|||:. :::..:|
 Worm   514 TSEETDKGSLWTFLEPLSLTVWISLLISYCIVSYSMHILAKFSPYEWYNLERIDERDFENIKNQK 578

  Fly   422 ----TLNFVW---GAMCQQGFYVEVRNRSARIIVFTTFVAALFLFTSFSANIVALL--QSPSDAI 477
                .||..|   |::.|||..|..|..:.|:|....::....:.:|::|.:.|.|  :..|..|
 Worm   579 NQFTVLNSFWFTMGSLMQQGSDVIPRAAATRLIAVVWWMFTQIIISSYTAQLAAFLTVERMSTPI 643

  Fly   478 QSLSDL-GQSPLEIGVQDTQYNKIYFTESTDPVTKNLYHKKIASKGENIYMRPLL-GMEKMRTGL 540
            :|..|| .|..:..||..:.....:|.||..|:.:.:: ..:.|....:::.... |:.::::|.
 Worm   644 ESTQDLANQQKIRYGVLKSGSTMDFFRESKIPMYERMW-SVMESSSPGVFVNSSREGIARVKSGG 707

  Fly   541 FAYQVE-LQAGYQIVSDTFSEPEKC------GLMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQ 598
            :||.:| ....|.:..|       |      ||::.:.:.   :|:|  |..|.::::.|.:...
 Worm   708 YAYMMESSMLEYYLERD-------CELQSIGGLLDSKGYG---IALP--KGSPLRDILSRTVLQL 760

  Fly   599 REVSLVNREERKWIPQK---PKCEGGVGGFVSIGITECRYALGIFG------CGAAVSFVLFLFE 654
            :|.:::...:.||...:   |.|    |...|...|..: ...|||      .|..|:|:|...|
 Worm   761 QERTILEALKNKWWRDRREGPSC----GPPPSEKATNSK-PQNIFGIFYVLLTGLIVAFLLACGE 820

  Fly   655 FIFRHFKQVYRI 666
            :......:.:|:
 Worm   821 YCIESRHEAFRL 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	49/209 (23%)
		Lig_chan	388..644	CDD:278489	63/294 (21%)
glr-4	NP_001254126.1	PBP1_iGluR_Kainate	30..385	CDD:107377	63/374 (17%)
		ANF_receptor	45..365	CDD:279440	58/339 (17%)
		Periplasmic_Binding_Protein_Type_2	410..775	CDD:304360	78/377 (21%)
		Lig_chan	533..810	CDD:278489	63/294 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010